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. 2022 Jan;145(1):53-62.
doi: 10.1111/ane.13521. Epub 2021 Aug 24.

Characteristics of sagittal spinopelvic alignment in patients with Parkinson's disease

Hiroo Terashi  1 , Kenji Endo  2 , Haruhisa Kato  1 , Nobuhiro Ido  1 , Hitoshi Aizawa  1
Affiliations

Characteristics of sagittal spinopelvic alignment in patients with Parkinson's disease

Hiroo Terashi et al. Acta Neurol Scand. 2022 Jan.

Abstract

Introduction: The aim of this study was to characterize the associations between sagittal spinopelvic alignment and motor symptoms in patients with Parkinson's disease (PD).

Methods: The study included patients with idiopathic PD (aged <80 years and with abnormal posture). All patients underwent whole-spine lateral and coronal radiography. Sagittal spinopelvic alignment was evaluated using nine parameters. Motor symptoms were evaluated using the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III score-with bradykinesia and axial motor sub-scores. Multivariate analysis was used to analyze associations between motor symptoms and sagittal spinopelvic alignment in PD patients according to sex.

Results: The study subjects were 79 PD patients (39 men, 40 women; median age, 70 years). Clear sex-related differences were noted. In male patients, the MDS-UPDRS part III score correlated significantly with cervical sagittal vertical axis (SVA), and bradykinesia and axial motor scores correlated significantly with SVA, cervical SVA, and T1 slope. In female patients, the MDS-UPDRS part III score correlated significantly with thoracic kyphosis, bradykinesia score correlated significantly with cervical SVA and thoracic kyphosis, and the axial motor score correlated significantly with SVA, cervical SVA, T1 slope, sacral slope, and pelvic tilt.

Conclusion: Our results showed clear correlations among various motor symptoms and sagittal global alignment in PD patients and that these correlations are different in female PD patients and their male counterparts.

Keywords: motor symptoms; parkinson disease; postural deformity; sagittal spinopelvic alignment.

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Conflict of interest statement

The authors declare no conflict of interest in relation to this study.

Figures

FIGURE 1
FIGURE 1
Radiographic parameters of sagittal alignment. SVA, sagittal vertical axis
See this image and copyright information in PMC

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