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. 2021 Dec 1;105(12):e280-e281.
doi: 10.1097/TP.0000000000003934.

Antibody Response to a Fourth Dose of a SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series

Jennifer L Alejo  1 , Jonathan Mitchell  1 , Teresa P-Y Chiang  1 , Aura T Abedon  1 , Brian J Boyarsky  1 , Robin K Avery  2 , Aaron A R Tobian  3 , Macey L Levan  1 , Allan B Massie  1 , Jacqueline M Garonzik-Wang  1 , Dorry L Segev  1 , William A Werbel  2
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Antibody Response to a Fourth Dose of a SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series

Jennifer L Alejo et al. Transplantation. .

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Conflict of interest statement

D.L.S. has received consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, and Thermo Fisher Scientific. M.L.L. is the Social Media Editor for Transplantation. The other authors declare no conflicts of interest. J.L.A., J.M., T.P.-Y.C., A.T.A., B.J.B., R.K.A., A.A.R.T., M.L.L., A.B.M., J.M.G.-W., D.L.S., and W.A.W. participated in conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; drafting the work of revising it critically for important intellectual content; gave the final approval of the version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

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References

    1. Boyarsky BJ, Werbel WA, Avery RK, et al. . Antibody response to 2-dose SARS-CoV-2 mRNA vaccine series in solid organ transplant recipients. JAMA. 2021;325:2204–2206. - PMC - PubMed
    1. Tau N, Yahav D, Schneider S, et al. . Severe consequences of COVID-19 infection among vaccinated kidney transplant recipients. Am J Transplant. 2021;21:2910–2912. - PMC - PubMed
    1. Qin CX, Moore LW, Anjan S, et al. . Risk of breakthrough SARS-CoV-2 infections in adult transplant recipients. Transplantation. 2021;105:e265–e266. - PMC - PubMed
    1. Werbel WA, Boyarsky BJ, Ou MT, et al. . Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients: a case series. Ann Intern Med. 2021;174:1330–1332. - PMC - PubMed
    1. Khoury DS, Cromer D, Reynaldi A, et al. . Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat Med. 2021;27:1205–1211. - PubMed

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