Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Aug 23;15(8):e01518.
doi: 10.1213/XAA.0000000000001518.

Liposomal Bupivacaine for Pediatric Celiac Plexus Block: A Case Report of Refractory Constipation Management

Kyle J Morgan  1 , Hasmukh J Prajapati  2   3 , Michael J Frett  1
Affiliations
Case Reports

Liposomal Bupivacaine for Pediatric Celiac Plexus Block: A Case Report of Refractory Constipation Management

Kyle J Morgan et al. A A Pract. .

Abstract

Liposomal bupivacaine is a long-acting amide local anesthetic with a limited list of indications. At the time of publication, use is limited to field block and surgical wound infiltration and, more recently, interscalene nerve block. Although commonly used in adults, less is known about the safety and efficacy in pediatric patients. We present the use of liposomal bupivacaine for pediatric celiac plexus block in a 12-year-old boy suffering from gastrointestinal complications (eg, pain, constipation, and ileus) after bone marrow transplantation. Celiac plexus block utilizing liposomal bupivacaine was successfully used to palliate his pain and to normalize bowel function.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Day KM, Nair NM, Sargent LA. Extended release liposomal bupivacaine injection (exparel) for early postoperative pain control following palatoplasty. J Craniofac Surg. 2018;29:e525–e528.
    1. Cohen B, Glosser L, Saab R, et al. Incidence of adverse events attributable to bupivacaine liposome injectable suspension or plain bupivacaine for postoperative pain in pediatric surgical patients: a retrospective matched cohort analysis. Paediatr Anaesth. 2019;29:169–174.
    1. Vandepitte C, Kuroda M, Witvrouw R, et al. Addition of liposome bupivacaine to bupivacaine HCl versus bupivacaine HCl alone for interscalene brachial plexus block in patients having major shoulder surgery. Reg Anesth Pain Med. 2017;42:334–341.
    1. Hadzic A, Minkowitz HS, Melson TI, et al. Liposome bupivacaine femoral nerve block for postsurgical analgesia after total knee arthroplasty. Anesthesiology. 2016;124:1372–1383.
    1. Kelley TM Jr, Bailey DW, Sparks P, et al. Intercostal nerve blockade with exparel® results in lower opioid usage during the first 24 hours after video-assisted thorascopic surgery. Am Surg. 2018;84:1433–1438.

Publication types

LinkOut - more resources