ASO Author Reflections: Identifying pCR After Neoadjuvant Chemotherapy: The Key to Treatment De-escalation in Breast Cancer

David W Lim^{1

2

3}, Nicole J Look Hong^{4

5

6}

Affiliations

¹ Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada. David.Lim@wchospital.ca.
² Department of Surgery, Women's College Hospital, Toronto, ON, Canada. David.Lim@wchospital.ca.
³ Division of General Surgery, Department of Surgery, University Health Network, Toronto, ON, Canada. David.Lim@wchospital.ca.
⁴ Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
⁵ Evaluative Clinical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute, Toronto, ON, Canada.
⁶ Division of Surgical Oncology, Sunnybrook Odette Cancer Centre, Toronto, ON, Canada.

Comment

David W Lim et al. Ann Surg Oncol. 2022 Dec.

. 2022 Dec;29(Suppl 3):570-571.

doi: 10.1245/s10434-021-10699-3. Epub 2021 Aug 25.

David W Lim^{1

2

3}, Nicole J Look Hong^{4

5

6}

¹ Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada. David.Lim@wchospital.ca.
² Department of Surgery, Women's College Hospital, Toronto, ON, Canada. David.Lim@wchospital.ca.
³ Division of General Surgery, Department of Surgery, University Health Network, Toronto, ON, Canada. David.Lim@wchospital.ca.
⁴ Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
⁵ Evaluative Clinical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute, Toronto, ON, Canada.
⁶ Division of Surgical Oncology, Sunnybrook Odette Cancer Centre, Toronto, ON, Canada.

No abstract available

Comment on

Relationship Between Breast and Axillary Pathologic Complete Response in Women Receiving Neoadjuvant Chemotherapy for Breast Cancer.
Lim DW, Greene BD, Look Hong NJ. Lim DW, et al. Ann Surg Oncol. 2021 Oct;28(10):5495-5506. doi: 10.1245/s10434-021-10519-8. Epub 2021 Aug 10. Ann Surg Oncol. 2021. PMID: 34374914

1. Kuerer HM, Newman LA, Buzdar AU, et al. Pathologic tumor response in the breast following neoadjuvant chemotherapy predicts axillary lymph node status. Cancer J Sci Am. 1998;4(4): 230–6.
1. Barron AU, Hoskin TL, Day CN, Hwang ES, Kuerer HM, Boughey JC. Association of low nodal positivity rate among patients with ERBB2-positive or triple-negative breast cancer and breast pathologic complete response to neoadjuvant chemotherapy. JAMA Surg. 2018;153(12):1120–6. - DOI - PubMed - PMC
1. Samiei S, van Nijnatten TJA, de Munck L, et al. Correlation between pathologic complete response in the breast and absence of axillary lymph node metastases after neoadjuvant systemic therapy. Ann Surg. 2020;271(3):574–80.
1. Lim DW, Greene BD, Look Hong NJ. Relationship between breast and axillary pathologic complete response in women receiving neoadjuvant chemotherapy for breast cancer. Ann Surg Oncol. 2021. https://doi.org/10.1245/s10434-021-10519-8 . - DOI - PubMed - PMC
1. Heil J, Kuerer HM, Pfob A, et al. Eliminating the breast cancer surgery paradigm after neoadjuvant systemic therapy: current evidence and future challenges. Ann Oncol. 2020;31(1):61–71.