Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan;14(1):41-46.
doi: 10.1111/luts.12407. Epub 2021 Aug 26.

Impact of COVID-19 pandemic on lower urinary tract symptoms in patients with benign prostatic hyperplasia and predictors of urine retention in such patients

Hossam Nabeeh  1 , Ali Ibrahim  1 , Diaa-Eldin Taha  1 , Mona Talaat  2 , Tarek M Abdelbaky  1
Affiliations

Impact of COVID-19 pandemic on lower urinary tract symptoms in patients with benign prostatic hyperplasia and predictors of urine retention in such patients

Hossam Nabeeh et al. Low Urin Tract Symptoms. 2022 Jan.

Abstract

Objectives: We assess the effect of coronavirus disease 2019 (COVID-19) on lower urinary tract symptoms (LUTS) of patients with benign prostatic hyperplasia (BPH). Moreover, we delineate risk factors for urine retention in such patients.

Methods: All COVID-19 infected males were expeditiously evaluated. All enrolled patients were assessed using the International Prostate Symptom Score (IPSS), uroflowmetry, and pelvi-abdominal ultrasonography for prostate volume and postvoiding residual urine (PVR) estimation.

Results: Fifty patients, who were diagnosed with BPH, were enrolled. The mean age (±SD) was 62.64 ± 7.69. In the pre- and post-COVID-19 group, the mean (±SD) IPSS was 13.42 ± 4.32 and 26.62 ± 5.77, respectively (P < .001), while PVR was 90.40 ± 32.75 and 185.42 ± 73.42, respectively (P < .001), and maximum flow rate was 14.40 ± 2.75 and 10.74 ± 3.43, respectively (P < .004). After infection with COVID-19, 13 (26%) patients were managed by urethral catheter fixation owing to urine retention. On bivariate analysis, age, diabetes, large prostate on digital rectal examination, alpha-blocker monotherapy, microscopic hematuria, positive urine culture, and pre-COVID-19 IPSS were significantly correlated with urine retention (P < .001, P = .01, P < .001, P = .06, P < .001, P = .04, and P < .001, respectively). On multivariate analysis, age, pre-COVID-19 IPSS, and positive urine culture were the independent predictors of urine retention (P = .05, P < .001, and P = .01, respectively).

Conclusion: LUTS in BPH patients were significantly affected by COVID-19. COVID-19 increases IPSS leading to a change in the treatment modality of BPH. On multivariate analysis, age, pre-COVID-19 IPSS, and positive urine culture were the independent predictors of urine retention post COVID-19 infection.

Keywords: COVID-19 pandemic; benign prostatic hyperplasia; lower urinary tract symptoms; urine retention.

PubMed Disclaimer

References

    1. Abrams P, Cardozo L, Fall M, et al. Standardisation sub‐committee of the international continence society the standardisation of terminology of lower urinary tract function: report from the standardisation sub‐committee of the international continence society. J Neurourol Urodyn. 2002;21:167‐178. - PubMed
    1. McNicholas T, Kirby R. Benign prostatic hyperplasia and male lower urinary tract symptoms. J Am Family Phys. 2012;86:359‐360. - PubMed
    1. Langan RC. Benign prostatic hyperplasia. J Prim Care. 2019;46:223‐232. - PubMed
    1. World Health Organization . Coronavirus Disease (COVID‐2019) Situation Reports. Geneva: World Health Organization; 2020.
    1. Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061‐1069. - PMC - PubMed