Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Aug 26;10(34):e0042721.
doi: 10.1128/MRA.00427-21. Epub 2021 Aug 26.

BK Polyomavirus Subtypes IVc-1 and Ib-1 in Vietnamese Renal Transplant Recipients

Hang Thi Thu Dinh  1 , Son Anh Ho  1 , Toan Quoc Pham  2 , Su Xuan Hoang  1
Affiliations

BK Polyomavirus Subtypes IVc-1 and Ib-1 in Vietnamese Renal Transplant Recipients

Hang Thi Thu Dinh et al. Microbiol Resour Announc. .

Abstract

We report here the nearly complete genome sequences of two human BK polyomavirus (BKV) strains recovered from two Vietnamese renal allograft recipients and belonging to subtypes IVc1 (strain VN_PBK185) and Ib1 (strain VN_PBK212). The genome sequences of VN_PBK185 and VN_PBK212 were highly similar (99.9% nucleotide identity) to the reference BKV strains VNM-1 and VNM-9, respectively.

PubMed Disclaimer

Figures

FIG 1
FIG 1
Maximum likelihood tree (Tamura-Nei model) of the MEGA X software based on the complete genome sequences of the 2 strains obtained in this study and 11 reference strains, including the BKV Dunlop sequence (GenBank accession number V01108.1 or NC_001538). The reliability of the tree topology was estimated by using 1,000 bootstrap replicates. The scale bar represents nucleotide substitutions per site. The triangles indicate the strains from this study. The circles indicate the complete sequences of the reference BKV strains.
See this image and copyright information in PMC

References

    1. Ambalathingal GR, Francis RS, Smyth MJ, Smith C, Khanna R. 2017. BK polyomavirus: clinical aspects, immune regulation, and emerging therapies. Clin Microbiol Rev 30:503–528. doi:10.1128/CMR.00074-16. - DOI - PMC - PubMed
    1. Jenkins A, Govind S, Morris C, Berry N. 2019. Complete genome sequence of original material used to derive the WHO international standard for human polyomavirus BK DNA. Microbiol Resour Announc 8:e00911-19. doi:10.1128/MRA.00911-19. - DOI - PMC - PubMed
    1. Morel V, Martin E, Francois C, Helle F, Faucher J, Mourez T, Choukroun G, Duverlie G, Castelain S, Brochot E. 2017. A simple and reliable strategy for BK virus subtyping and subgrouping. J Clin Microbiol 55:1177–1185. doi:10.1128/JCM.01180-16. - DOI - PMC - PubMed
    1. Zhong S, Randhawa PS, Ikegaya H, Chen Q, Zheng H-Y, Suzuki M, Takeuchi T, Shibuya A, Kitamura T, Yogo Y. 2009. Distribution patterns of BK polyomavirus (BKV) subtypes and subgroups in American, European and Asian populations suggest co-migration of BKV and the human race. J Gen Virol 90:144–152. doi:10.1099/vir.0.83611-0. - DOI - PubMed
    1. Chen Q, Zheng H-Y, Zhong S, Ikegaya H, He H-X, Wei W, He Y-Y, Kobayashi N, Honjo T, Takasaka T, Takahashi S, Kitamura T, Yogo Y. 2006. Subtype IV of the BK polyomavirus is prevalent in East Asia. Arch Virol 151:2419–2429. doi:10.1007/s00705-006-0814-z. - DOI - PubMed

LinkOut - more resources