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Review
. 2022 Oct;289(19):5875-5890.
doi: 10.1111/febs.16168. Epub 2021 Sep 3.

The Enzyme Portal: an integrative tool for enzyme information and analysis

Rossana Zaru  1 , Joseph Onwubiko  1 , Antonio J M Ribeiro  1 , Keeva Cochrane  1 , Jonathan D Tyzack  1 , Venkatesh Muthukrishnan  1 , Lukas Pravda  1 , Janet M Thornton  1 , Claire O'Donovan  1 , Sameer Velanker  1 , Sandra Orchard  1 , Andrew Leach  1 , Maria J Martin  1
Affiliations
Free article
Review

The Enzyme Portal: an integrative tool for enzyme information and analysis

Rossana Zaru et al. FEBS J. 2022 Oct.
Free article

Abstract

Enzymes play essential roles in all life processes and are used extensively in the biomedical and biotechnological fields. However, enzyme-related information is spread across multiple resources making its retrieval time-consuming. In response to this challenge, the Enzyme Portal has been established to facilitate enzyme research, by providing a freely available hub where researchers can easily find and explore enzyme-related information. It integrates relevant enzyme data for a wide range of species from various resources such as UniProtKB, PDBe and ChEMBL. Here, we describe what type of enzyme-related data the Enzyme Portal provides, how the information is organized and, by show-casing two potential use cases, how to access and retrieve it.

Keywords: EC number; database; enzyme; metabolite.

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