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. 2021 Nov:130:410-432.
doi: 10.1016/j.neubiorev.2021.08.012. Epub 2021 Aug 23.

Rodent models used in preclinical studies of deep brain stimulation to rescue memory deficits

Matthieu Faillot  1 , Antoine Chaillet  2 , Stéphane Palfi  1 , Suhan Senova  3
Affiliations

Rodent models used in preclinical studies of deep brain stimulation to rescue memory deficits

Matthieu Faillot et al. Neurosci Biobehav Rev. 2021 Nov.

Abstract

Deep brain stimulation paradigms might be used to treat memory disorders in patients with stroke or traumatic brain injury. However, proof of concept studies in animal models are needed before clinical translation. We propose here a comprehensive review of rodent models for Traumatic Brain Injury and Stroke. We systematically review the histological, behavioral and electrophysiological features of each model and identify those that are the most relevant for translational research.

Keywords: Deep Brain Stimulation; Memory; Rodent; Stroke; Traumatic Brain Injury.

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