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Review
. 2021 Aug 14;26(16):4933.
doi: 10.3390/molecules26164933.

Can Eucalyptol Replace Antibiotics?

Wanda Mączka  1 , Anna Duda-Madej  2 , Aleksandra Górny  1 , Małgorzata Grabarczyk  1 , Katarzyna Wińska  1
Affiliations
Review

Can Eucalyptol Replace Antibiotics?

Wanda Mączka et al. Molecules. .

Abstract

One of the primary reasons for the search for new antimicrobial agents is the increasing and spreading resistance of microorganisms to previously used drugs. This is particularly important in the case of rapidly progressing infections that require the rapid administration of an appropriately selected antibiotic. However, along with the administration of antibiotics, complications in the disease-weakened body may arise in the form of systemic mycoses, viral infections, and protozoan infections. Therefore, there is an increasing interest among researchers focusing on the use of naturally occurring terpenic compounds in stand-alone or combined therapies with antibiotics. In this publication, the aim of our work is to present the results of a literature review on the antimicrobial activity of eucalyptol.

Keywords: 1,8-cineole; antimicrobial activity; eucalyptol.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Structure of 1,8-cineole.
Figure 2
Figure 2
Biotransformation of 1,8-cineole by CYP176A1 and CYP101A1 [105].
Figure 3
Figure 3
Spheres of wide use of eucalyptol (based on [106]).
See this image and copyright information in PMC

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