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Review
. 2021 Aug 5;22(16):8427.
doi: 10.3390/ijms22168427.

The Role of lncRNA in the Development of Tumors, including Breast Cancer

Beata Smolarz  1 , Anna Zadrożna-Nowak  2 , Hanna Romanowicz  1
Affiliations
Review

The Role of lncRNA in the Development of Tumors, including Breast Cancer

Beata Smolarz et al. Int J Mol Sci. .

Abstract

Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules seems to be of great importance for the proper functioning of the organism. Studies have shown a relationship between disturbed lncRNA expression and the pathogenesis of many diseases, including cancer. The present article presents a detailed review of the latest reports and data regarding the importance of lncRNA in the development of cancers, including breast carcinoma.

Keywords: breast cancer; expression; lncRNA; tumors.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Classification of lncRNA.
See this image and copyright information in PMC

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