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. 2021 May-Jun;66(3):302-307.
doi: 10.4103/ijd.IJD_728_20.

Skin and Metabolic Syndrome: An Evidence Based Comprehensive Review

Affiliations

Skin and Metabolic Syndrome: An Evidence Based Comprehensive Review

Farhat Fatima et al. Indian J Dermatol. 2021 May-Jun.

Abstract

Metabolic syndrome is currently considered to be a global epidemic, causing a significant increase in the cost of health care, apart from deteriorating the quality of life. Skin serves as a mirror of underlying metabolic sinister. Various dermatological conditions like psoriasis, acanthosis nigricans, lichen planus, acne vulgaris, acrochordons, atopic dermatitis, etc. have been reported to be associated with metabolic syndrome. We hereby present an evidence-based review of the various dermatological conditions and their association with the development of metabolic syndrome.

Keywords: Evidence-based review; metabolic syndrome; skin.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Pathophysiology of metabolic syndrome

References

    1. Hu Y, Zhu Y, Lian N, Chen M, Bartke A, Yuan R. Metabolic syndrome and skin diseases. Front Endocrinol (Lausanne) 2019;10:788. - PMC - PubMed
    1. Stefanadi EC, Dimitrakakis G, Antoniou CK, Challoumas D, Punjabi N, DImitrakaki IA, et al. Metabolic syndrome and the skin: A more than superficial association. Reviewing the association between skin diseases and metabolic syndrome and a clinical decision algorithm for high risk patients. Diabetol Metab Syndr. 2018;10:9. - PMC - PubMed
    1. Cleeman JI. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) J Am Med Assoc. 2001;285:2486–97. - PubMed
    1. Leroith D. Pathophysiology of the metabolic syndrome: Implications for the cardiometabolic risks associated with type 2 diabetes. Am J Med Sci. 2012;343:13–6. - PubMed
    1. Karadag AS, Lavery MJ. Skin and the metabolic syndrome. Clin Dermatol. 2018;36:1–2. - PubMed