Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun;13(Suppl 1):S120-S123.
doi: 10.4103/jpbs.JPBS_598_20. Epub 2021 Jun 5.

Evaluation of Preoperative Salivary Cortisol Level in Patients Undergoing Major Maxillofacial Surgery

Archana Kumari  1 , Praveen Chandra  2 , Sonali Roy  3 , Ritika Agarwal  4 , Aartika Singh  5 , Suprabha Sharan  6
Affiliations

Evaluation of Preoperative Salivary Cortisol Level in Patients Undergoing Major Maxillofacial Surgery

Archana Kumari et al. J Pharm Bioallied Sci. 2021 Jun.

Abstract

Aim: The main purpose of the study was to compare the preoperative salivary cortisol levels 3 days before the major surgery under general anesthesia and to compare it with the patients undergoing extraction under local anesthesia.

Materials and methods: Forty-two patients were undergoing major surgery and 42 age- and sex-matched patients undergoing dental extraction were included and their salivary cortisol levels were analyzed before and after the dental procedure.

Results: Results showed that there is a significant increase in the mean salivary cortisol concentration after extraction (23.7 ± 9.2) than before extraction (18.9 ± 23.7) in the study group (P = 0.015) as well as in the control group. The comparison between salivary cortisol in the study group before (18.9 ± 23.7) and after (23.7 ± 9.2) surgery was significantly higher than the control group (15.2 ± 5.5) (P = 0.013 and 0.005), respectively.

Conclusion: We have concluded from this study that the salivary cortisol level shows a significant increase on the day of surgery.

Keywords: Cortisol; dental anxiety; extraction; oral surgery.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Graph 1
Graph 1
Mean salivary cortisol values in males and females
Graph 2
Graph 2
Distribution of pathologies for which surgery was performed
See this image and copyright information in PMC

References

    1. Appukuttan DP. Strategies to manage patients with dental anxiety and dental phobia: Literature review. Clin Cosmet Investig Dent. 2016;8:35. - PMC - PubMed
    1. Oosterink FM, De Jongh A, Aartman IH. What are people afraid of during dental treatment. Anxiety-provoking capacity of 67 stimuli characteristic of the dental setting? Eur J Oral Sci. 2008;116:44–51. - PubMed
    1. Hmud R, Walsh LJ. Dental anxiety: Causes, complications and management approaches. J Minim Interv Dent. 2009;2:67–78.
    1. Greabu M, Purice M, Totan A, Spinu T, Totan C. Salivary cortisol-marker of stress response to different dental treatment. Rom J Intern Med. 2006;44:49. - PubMed
    1. Aher S, Waknis P, Shah S, Saha A, Bhujbal P, Gupta D. Evaluation of presurgical serum cortisol level in patients undergoing major maxillofacial surgery. Ann Maxillofac Surg. 2020;10:25. - PMC - PubMed

LinkOut - more resources