Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jul 30;14(8):752.
doi: 10.3390/ph14080752.

Nanoparticles in Dentistry: A Comprehensive Review

Gustavo Moraes  1   2 , Carolina Zambom  3 , Walter L Siqueira  1
Affiliations
Review

Nanoparticles in Dentistry: A Comprehensive Review

Gustavo Moraes et al. Pharmaceuticals (Basel). .

Abstract

In recent years, nanoparticles (NPs) have been receiving more attention in dentistry. Their advantageous physicochemical and biological properties can improve the diagnosis, prevention, and treatment of numerous oral diseases, including dental caries, periodontal diseases, pulp and periapical lesions, oral candidiasis, denture stomatitis, hyposalivation, and head, neck, and oral cancer. NPs can also enhance the mechanical and microbiological properties of dental prostheses and implants and can be used to improve drug delivery through the oral mucosa. This paper reviewed studies from 2015 to 2020 and summarized the potential applications of different types of NPs in the many fields of dentistry.

Keywords: dental caries; dental prosthesis; drug delivery; head and neck neoplasms; hyposalivation; nanoparticles; periodontal diseases.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Yakop F., Abd Ghafar S.A., Yong Y.K., Saiful Yazan L., Mohamad Hanafiah R., Lim V., Eshak Z. Silver nanoparticles Clinacanthus Nutans leaves extract induced apoptosis towards oral squamous cell carcinoma cell lines. Artif. Cells Nanomed. Biotechnol. 2018;46:131–139. doi: 10.1080/21691401.2018.1452750. - DOI - PubMed
    1. Rudramurthy G.R., Swamy M.K. Potential applications of engineered nanoparticles in medicine and biology: An update. J. Biol. Inorg. Chem. 2018;23:1185–1204. doi: 10.1007/s00775-018-1600-6. - DOI - PubMed
    1. Anu Mary Ealia S., Saravanakumar M.P. A review on the classification, characterisation, synthesis of nanoparticles and their application. IOP Conf. Ser. Mater. Sci. Eng. 2017;263:032019. doi: 10.1088/1757-899X/263/3/032019. - DOI
    1. Meena A., Mali H.S., Patnaik A., Kumar S.R. Comparative investigation of physical, mechanical and thermomechanical characterization of dental composite filled with nanohydroxyapatite and mineral trioxide aggregate. e-Polymers. 2017;17:311–319. doi: 10.1515/epoly-2016-0319. - DOI
    1. Omidi M., Fatehinya A., Farahani M., Akbari Z., Shahmoradi S., Yazdian F., Tahriri M., Moharamzadeh K., Tayebi L., Vashaee D. Characterization of Biomaterials. Elsevier; Singapore: 2017. pp. 97–115.

LinkOut - more resources