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. 2021 Aug 28;19(1):55.
doi: 10.1186/s12962-021-00307-2.

Comparison of cost effectiveness between video-assisted thoracoscopic surgery (vats) and open lobectomy: a retrospective study

Wei Chen  1 , Zhanwu Yu  1 , Yichen Zhang  2 , Hongxu Liu  3
Affiliations

Comparison of cost effectiveness between video-assisted thoracoscopic surgery (vats) and open lobectomy: a retrospective study

Wei Chen et al. Cost Eff Resour Alloc. .

Abstract

Background: Lung cancer is highly prevalent in Chinese population. The association of operative approach with economic burden in these patients remains unknown.

Objectives: This institution-level cohort study aimed to compare the cost-related clinical outcomes and health care costs among patients undergoing video-assisted thoracoscopic surgery (VATS) and open lobectomy, and to investigate the factors associated with the costs.

Methods: This retrospective cohort study included patients who underwent VATS or open lobectomy in a provincial referral cancer center in China in 2018. Propensity score matching (PSM) method was applied to balance the baseline characteristics in VATS lobectomy and open lobectomy group. Clinical effectiveness measures included post-operative blood transfusion, lung infection, and length of stay (LOS). Hospitalization costs were extracted from hospital information system to assess economic burden. Multivariable generalized linear model (GLM) with gamma probability distribution and log-link was used to analyze the factors associated with total costs.

Results: After PSM, 376 patients were selected in the analytic sample. Compared to open lobectomy group, the VATS lobectomy group had a lower blood transfusion rate (2.13% vs. 3.19%, P = 0.75), lower lung infection rate (21.28% vs. 39.89%, P < 0.001) and shorter post-operative LOS (9.4 ± 3.22 days vs. 10.86 ± 4.69 days, P < 0.001). Total hospitalization costs of VATS lobectomy group and open lobectomy were similar: Renminbi (RMB) 84398.03 ± 13616.13, RMB 81,964.92 ± 16748.11, respectively (P = 0.12). Total non-surgery costs were significantly lower in the VATS lobectomy group than in the open lobectomy group: RMB 41948.40 ± 7747.54 vs. RMB 45752.36 ± 10346.42 (P < 0.001). VATS approach, lung infection, longer post-operative length of stay, health insurance coverage, and lung cancer diagnosis were associated with higher total hospitalization costs (P < 0.05).

Conclusions: VATS lobectomy has a lower lung infection rate, and shorter post-operative LOS than open lobectomy. Future studies are needed to investigate other aspects of clinical effectiveness and the economic burden from a societal perspective.

Keywords: Cost effectiveness; Lung cancer; Open lobectomy; Video-Assisted Thoracoscopic Surgery (VATS).

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Conflict of interest statement

This study was funded by the following funding sources to WC, ZY, and HX. YZ declares no competing interests.

Figures

Fig. 1
Fig. 1
Sample selection flow chart
Fig. 2
Fig. 2
Cost breakdown comparisons between VATS and open lobectomy procedures
See this image and copyright information in PMC

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References

    1. Global Cancer Observatory: Cancer Today. International Agency for Research on Cancer. World Health Organization. https://gco.iarc.fr/today/data/factsheets/populations/160-china-fact-she.... Accessed 24 Aug 2021.
    1. Lobectomy. American Lung Association. 2020. https://www.lung.org/lung-health-diseases/lung-procedures-and-tests/lobe.... 19 Feb 2020.
    1. Minimally Invasive Thoracic Surgery. American Lung Association. 2020. https://www.lung.org/lung-health-diseases/lung-procedures-and-tests/mini.... 13 April 2020.
    1. Paul S, Altorki NK, Sheng S, et al. Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database. J Thorac Cardiovasc Surg. 2010;139(2):366–378. doi: 10.1016/j.jtcvs.2009.08.026. - DOI - PubMed
    1. Swanson SJ, Meyers BF, Gunnarsson CL, et al. Video-assisted thoracoscopic lobectomy is less costly and morbid than open lobectomy: a retrospective multi-institutional database analysis. Ann Thorac Surg. 2012;93(4):1027–1032. doi: 10.1016/j.athoracsur.2011.06.007. - DOI - PubMed

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