How necessary are animal models for modern drug discovery?
- PMID: 34455867
- DOI: 10.1080/17460441.2021.1972255
How necessary are animal models for modern drug discovery?
Similar articles
-
Cell and small animal models for phenotypic drug discovery.Drug Des Devel Ther. 2017 Jun 28;11:1957-1967. doi: 10.2147/DDDT.S129447. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 28721015 Free PMC article. Review.
-
Zebrafish: a complete animal model for in vivo drug discovery and development.Curr Drug Metab. 2009 Feb;10(2):116-24. doi: 10.2174/138920009787522197. Curr Drug Metab. 2009. PMID: 19275547 Review.
-
[The Usefulness of Silkworms as a Model Animal for Evaluating the Effectiveness of Medicine and Food].Yakugaku Zasshi. 2017;137(5):551-562. doi: 10.1248/yakushi.16-00249. Yakugaku Zasshi. 2017. PMID: 28458287 Review. Japanese.
-
A New Approach to Optimising the Use of Animal Models in Drug Discovery through Big Data Sharing.Altern Lab Anim. 2015 Nov;43(5):P55-8. doi: 10.1177/026119291504300517. Altern Lab Anim. 2015. PMID: 26551292 No abstract available.
-
Improving productivity of modern-day drug discovery.Expert Opin Drug Discov. 2014 Feb;9(2):115-8. doi: 10.1517/17460441.2014.870150. Epub 2013 Dec 12. Expert Opin Drug Discov. 2014. PMID: 24328737
Cited by
-
Animal Models in Regulatory Breakpoint Determination: Review of New Drug Applications of Approved Antibiotics from 2014-2022.J Pers Med. 2024 Jan 19;14(1):111. doi: 10.3390/jpm14010111. J Pers Med. 2024. PMID: 38276233 Free PMC article.
-
Gut-on-a-chip models for dissecting the gut microbiology and physiology.APL Bioeng. 2023 Feb 28;7(1):011502. doi: 10.1063/5.0126541. eCollection 2023 Mar. APL Bioeng. 2023. PMID: 36875738 Free PMC article. Review.
-
CryoGrid-PIXUL-RNA: high throughput RNA isolation platform for tissue transcript analysis.BMC Genomics. 2023 Aug 8;24(1):446. doi: 10.1186/s12864-023-09527-7. BMC Genomics. 2023. PMID: 37553584 Free PMC article.
-
Streptozotocin as a tool for induction of rat models of diabetes: a practical guide.EXCLI J. 2023 Feb 21;22:274-294. doi: 10.17179/excli2022-5720. eCollection 2023. EXCLI J. 2023. PMID: 36998708 Free PMC article. Review.
-
Microfluidic platforms for monitoring cardiomyocyte electromechanical activity.Microsyst Nanoeng. 2025 Jan 9;11(1):4. doi: 10.1038/s41378-024-00751-z. Microsyst Nanoeng. 2025. PMID: 39788940 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources