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Review
. 2022 May;21(3):387-395.
doi: 10.1016/j.jcf.2021.07.019. Epub 2021 Aug 26.

Pregnancy in cystic fibrosis: Review of the literature and expert recommendations

Raksha Jain  1 , Traci M Kazmerski  2 , Lisa C Zuckerwise  3 , Natalie E West  4 , Kristina Montemayor  4 , Moira L Aitken  5 , Edith Cheng  6 , Andrea H Roe  7 , Alexandra Wilson  8 , Caitlin Mann  3 , Sigrid Ladores  9 , Jacqui Sjoberg  10 , Madeline Poranski  11 , Jennifer L Taylor-Cousar  12
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Free article
Review

Pregnancy in cystic fibrosis: Review of the literature and expert recommendations

Raksha Jain et al. J Cyst Fibros. 2022 May.
Free article

Abstract

Cystic fibrosis (CF) was historically a disease largely afflicting children. Due to therapeutic advancements, there are now more adults with CF than children. In the past decade, medications including Cystic Fibrosis Transmembrane conductance Regulator (CFTR) modulators became available that treat the underlying cause of CF and are dramatically improving lung function as well as quality and quantity of life for people with CF. As a result, more women with CF are becoming pregnant. We gathered a panel of experts in CF care, family planning, high risk obstetrics, nutrition, genetics and women with CF to review current literature on pregnancies and to provide care recommendations for this unique population.

Keywords: Cystic fibrosis; Family planning; Fertility; Parenthood; Pregnancy.

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Conflict of interest statement

Declaration of Competing Interest JT, RJ, NW, MA and TK received grant funding from the CF Foundation for the Women's Health Research Working Group related to this work. Conflicts of interest unrelated to this work are included in a supplemental document.

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