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. 2021 Aug 30;105(5):1339-1346.
doi: 10.4269/ajtmh.21-0113.

Prevalence and Factors Associated with Maternal Group B Streptococcus Colonization in Madagascar and Senegal

Yu-Jin Jung, Bich-Tram Huynh, Abdoulaye Seck, Raymond Bercion, Fatoumata Diene Sarr, Perlinot Herindrainy, Jean-Baptiste Diouf, Zafitsara Zo Andrianirina, Arnaud Firon, Patrick Trieu-Cuot, Sophie Goyet, Jean-Marc Collard, Elisabeth Delarocque-Astagneau, Didier Guillemot, Muriel Vray; BIRDY Study Group

Prevalence and Factors Associated with Maternal Group B Streptococcus Colonization in Madagascar and Senegal

Yu-Jin Jung et al. Am J Trop Med Hyg. .

Abstract

Maternal group B Streptococcus (GBS) colonization is a major risk factor for neonatal GBS infection. However, data on GBS are scarce in low- and middle-income countries. Using sociodemographic data and vaginal swabs collected from an international cohort of mothers and newborns, this study aimed to estimate the prevalence of GBS colonization among pregnant women in Madagascar (n = 1,603) and Senegal (n = 616). The prevalence was 5.0% (95% CI, 3.9-6.1) and 16.1% (95% CI, 13.1-19.0) in Madagascar and Senegal, respectively. No factors among sociodemographic characteristics, living conditions, and obstetric history were found to be associated independently with GBS colonization in both countries. This community-based study provides one of the first estimates of maternal GBS colonization among pregnant women from Madagascar and Senegal.

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Figures

Figure 1.
Figure 1.
Study sites maps. This figure appears in color at www.ajtmh.org.
Figure 2.
Figure 2.
Madagascar flowchart.
Figure 3.
Figure 3.
Senegal flowchart.
See this image and copyright information in PMC

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