[Plastic restructuring of cerebral cortex synapses in the postischemic period]

Abstract

Using the technique for the cerebral tissue contrasting with phosphoric-tungsten acid, synaptic architectonics of the molecular layer of the rat sensomotor cortex has been studied for 30 days of recirculation after 5 minutes' stop of the systemic circulation resulted from an acute hemorrhage. Gradation of the synapses per groups is performed according to the height of compact projections of the presynaptic network. Dynamics of the synaptic compactness changes with different height is stated to differ essentially during the postischemic period. A conclusion is made that in reconstruction of the synaptic architectonics of the neocortex during the postischemic period a leading role belongs to the change of state of specialized paramembranous microfilamentous compact projections of the presynaptic network. They make a part of the neuronal cytoskeleton and are included into a single integral complex--the system of subcytoskeleton and are included into a single integral complex--the system of subsynaptic units.