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. 2021 Aug 30;21(1):253.
doi: 10.1186/s12911-021-01608-5.

Modeling and prediction of pressure injury in hospitalized patients using artificial intelligence

Christine Anderson #  1 , Zerihun Bekele #  2 , Yongkai Qiu  3 , Dana Tschannen  4 , Ivo D Dinov  5   6   7   8
Affiliations

Modeling and prediction of pressure injury in hospitalized patients using artificial intelligence

Christine Anderson et al. BMC Med Inform Decis Mak. .

Abstract

Background: Hospital-acquired pressure injuries (PIs) induce significant patient suffering, inflate healthcare costs, and increase clinical co-morbidities. PIs are mostly due to bed-immobility, sensory impairment, bed positioning, and length of hospital stay. In this study, we use electronic health records and administrative data to examine the contributing factors to PI development using artificial intelligence (AI).

Methods: We used advanced data science techniques to first preprocess the data and then train machine learning classifiers to predict the probability of developing PIs. The AI training was based on large, incongruent, incomplete, heterogeneous, and time-varying data of hospitalized patients. Both model-based statistical methods and model-free AI strategies were used to forecast PI outcomes and determine the salient features that are highly predictive of the outcomes.

Results: Our findings reveal that PI prediction by model-free techniques outperform model-based forecasts. The performance of all AI methods is improved by rebalancing the training data and by including the Braden in the model learning phase. Compared to neural networks and linear modeling, with and without rebalancing or using Braden scores, Random forest consistently generated the optimal PI forecasts.

Conclusions: AI techniques show promise to automatically identify patients at risk for hospital acquired PIs in different surgical services. Our PI prediction model provide a first generation of AI guidance to prescreen patients at risk for developing PIs.

Clinical impact: This study provides a foundation for designing, implementing, and assessing novel interventions addressing specific healthcare needs. Specifically, this approach allows examining the impact of various dynamic, personalized, and clinical-environment effects on PI prevention for hospital patients receiving care from various surgical services.

Keywords: Clinical assessment; Health analytics; Human–machine intelligence; Precision medicine.

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Conflict of interest statement

None of the authors declares any conflicts of interest.

Figures

Fig. 1
Fig. 1
Graphical flowchart illustrating the end-to-end pipeline process from ingesting the raw data, through the preprocessing, modeling, analysis, prediction, and visualization of the results
Fig. 2
Fig. 2
Model evaluation metrics
See this image and copyright information in PMC

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