Statins After Variceal Bleeding Are Beneficial, but Still an Unexplained Mystery?

Affiliations

¹ Internal Medicine Department, Fluminense Federal University, Niteroi, Rio de Janeiro, Brazil; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil.
² Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark; European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain.

Comment

Priscilla Pollo-Flores et al. Gastroenterology. 2021 Dec.

. 2021 Dec;161(6):2067-2068.

doi: 10.1053/j.gastro.2017.01.065. Epub 2021 Aug 28.

¹ Internal Medicine Department, Fluminense Federal University, Niteroi, Rio de Janeiro, Brazil; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil.
² Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark; European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain.

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Dige A, Hougaard HT, Agnholt J, Pedersen BG, Tencerova M, Kassem M, Krogh K, Lundby L. Dige A, et al. Gastroenterology. 2021 Dec;161(6):2068-2069. doi: 10.1053/j.gastro.2019.09.057. Epub 2021 Sep 8. Gastroenterology. 2021. PMID: 34506755 No abstract available.

Addition of Simvastatin to Standard Therapy for the Prevention of Variceal Rebleeding Does Not Reduce Rebleeding but Increases Survival in Patients With Cirrhosis.
Abraldes JG, Villanueva C, Aracil C, Turnes J, Hernandez-Guerra M, Genesca J, Rodriguez M, Castellote J, García-Pagán JC, Torres F, Calleja JL, Albillos A, Bosch J; BLEPS Study Group. Abraldes JG, et al. Gastroenterology. 2016 May;150(5):1160-1170.e3. doi: 10.1053/j.gastro.2016.01.004. Epub 2016 Jan 14. Gastroenterology. 2016. PMID: 26774179 Clinical Trial.