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Comment
. 2021 Aug 17;2(8):100377.
doi: 10.1016/j.xcrm.2021.100377.

A protein regulated by UBE3A PEGs a potential biomarker

Noelle D Germain  1 , Stormy J Chamberlain  1   2
Affiliations
Comment

A protein regulated by UBE3A PEGs a potential biomarker

Noelle D Germain et al. Cell Rep Med. .

Abstract

New research from Pandya and colleagues1 identifies PEG10 as a UBE3A-regulated protein that may underlie pathophysiology in Angelman syndrome neurons. PEG10 is a secreted protein, and this work suggests that it may be a potential biomarker for Angelman syndrome therapeutics under development.

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Conflict of interest statement

The authors have a patent application (PCT/US19/52272) related to Angelman syndrome therapeutics and a financial conflict of interest with Ovid Therapeutics.

Comment on

References

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