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Comment
. 2021 Aug 17;2(8):100378.
doi: 10.1016/j.xcrm.2021.100378.

Psychotherapy-supported MDMA treatment for PTSD

John H Krystal  1   2 , Benjamin Kelmendi  1   2 , Ismene L Petrakis  1   2
Affiliations
Comment

Psychotherapy-supported MDMA treatment for PTSD

John H Krystal et al. Cell Rep Med. .

Abstract

A promising new Phase III study of MDMA plus psychotherapy for PTSD treatment by Mitchell and colleagues that appeared in Nature Medicine raises important new questions about the biology and optimal treatment of this disorder.

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Conflict of interest statement

Financial disclosures can be found in the supplemental information.

Comment on

  • MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study.
    Mitchell JM, Bogenschutz M, Lilienstein A, Harrison C, Kleiman S, Parker-Guilbert K, Ot'alora G M, Garas W, Paleos C, Gorman I, Nicholas C, Mithoefer M, Carlin S, Poulter B, Mithoefer A, Quevedo S, Wells G, Klaire SS, van der Kolk B, Tzarfaty K, Amiaz R, Worthy R, Shannon S, Woolley JD, Marta C, Gelfand Y, Hapke E, Amar S, Wallach Y, Brown R, Hamilton S, Wang JB, Coker A, Matthews R, de Boer A, Yazar-Klosinski B, Emerson A, Doblin R. Mitchell JM, et al. Nat Med. 2021 Jun;27(6):1025-1033. doi: 10.1038/s41591-021-01336-3. Epub 2021 May 10. Nat Med. 2021. PMID: 33972795 Free PMC article. Clinical Trial.

References

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