Assessing the Full Burden of Respiratory Syncytial Virus in Young Infants in Low- and Middle-Income Countries: The Importance of Community Mortality Studies
- PMID: 34472571
- PMCID: PMC8411251
- DOI: 10.1093/cid/ciab486
Assessing the Full Burden of Respiratory Syncytial Virus in Young Infants in Low- and Middle-Income Countries: The Importance of Community Mortality Studies
Abstract
The Bill & Melinda Gates Foundation supported respiratory syncytial virus (RSV) mortality surveillance studies in several low- and middle-income countries to address the striking gap in community mortality burden data from these geographies. The compelling findings generated from these studies reveal a high unmeasured burden of community RSV mortality, particularly among infants aged <6 months who are the target population for RSV immunization products currently in late-stage clinical development. These findings should inform revised global RSV mortality estimates and inform policy decisions on RSV vaccine financing and prioritization at the global and national levels.
Keywords: burden; community mortality; respiratory syncytial virus.
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.
References
-
- Geoghegan S, Erviti A, Caballero MT, et al. . Mortality due to respiratory syncytial virus. Burden and risk factors. Am J Respir Crit Care Med 2017; 195:96–103. - PubMed
-
- Shi T, McAllister DA, O’Brien KL, et al. ; RSV Global Epidemiology Network . Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet 2017; 390:946–58. - PMC - PubMed
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