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Clinical Trial
. 1987:85:238-53.

A prospective, randomized study of 5-fluorouracil and filtration surgery

J M Ruderman  1 , D B Welch, M F Smith, D E Shoch
Affiliations
Clinical Trial

A prospective, randomized study of 5-fluorouracil and filtration surgery

J M Ruderman et al. Trans Am Ophthalmol Soc. 1987.

Abstract

Our study shows that use of a small dose of subconjunctival 5-FU provides significantly lower postoperative intraocular pressure than does no antimetabolite treatment. Morphology of the postoperative blebs suggests that increased filtration results in lower intraocular pressure in the 5-FU group. Corneal epithelial defects were as common with a low dose as with higher doses previously described.

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References

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    1. Ophthalmology. 1984 Apr;91(4):378-83 - PubMed
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