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. 2021 Sep 2;16(9):e0253639.
doi: 10.1371/journal.pone.0253639. eCollection 2021.

Coronary heart disease and stroke mortality trends in Brazil 2000-2018

Patrícia Vasconcelos Leitão Moreira  1 , Adélia da Costa Pereira de Arruda Neta  1 , Sara Silva Ferreira  1 , Flávia Emília Leite Lima Ferreira  1 , Rafaela Lira Formiga Cavalcanti de Lima  1 , Rodrigo Pinheiro de Toledo Vianna  1 , Jevuks Matheus de Araújo  2 , Rômulo Eufrosino de Alencar Rodrigues  2 , José Moreira da Silva Neto  3 , Martin O'Flaherty  4
Affiliations

Coronary heart disease and stroke mortality trends in Brazil 2000-2018

Patrícia Vasconcelos Leitão Moreira et al. PLoS One. .

Abstract

Objective: To analyse the mortality rate trend due to coronary heart disease (CHD) and stroke in the adult population in Brazil.

Methods: From 2000 to 2018, a time trend study with joinpoint regression was conducted among Brazilian men and women aged 35 years and over. Age-adjusted and age, sex specific CHD and stroke trend rate mortality were measured.

Results: Crude mortality rates from CHD decreased in both sexes and in all age groups, except for males over 85 years old with an increase of 1.78%. The most accentuated declining occurred for age range 35 to 44 years for both men (52.1%) and women (53.2%) due to stroke and in men (33%) due to CHD, and among women (32%) aged 65 to 74 years due to CHD. Age-adjusted mortality rates for CHD and stroke decreased in both sexes, in the period from 2000 to 2018. The average annual rate for CHD went from 97.09 during 2000-2008 to 78.75 during 2016-2018, whereas the highest percentage of change was observed during 2008 to 2013 (APC -2.5%; 95% CI). The average annual rate for stroke decreased from 104.96 to 69.93, between 2000-2008 and 2016-2018, and the highest percentage of change occurred during the periods from 2008 to 2013 and 2016 to 2018 (APC 4.7%; 95% CI).

Conclusion: The downward trend CHD and stroke mortality rates is continuing. Policy intervention directed to strengthen care provision and improve population diets and lifestyles might explain the continued progress, but there is no room for complacency.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Trends in age-standardized mortality rates per 100,000 by sex for coronary heart disease and stroke.
Brazil. 2000–2018.
Fig 2
Fig 2. Trends in age and sex-specific mortality rates per 100,000 for coronary heart disease, Brazil.
2000–2018.
Fig 3
Fig 3. Trends in age and sex-specific mortality rates per 100,000 for stroke, Brazil.
2000–2018.
See this image and copyright information in PMC

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