. 2021 Sep 2;15(9):e0009661.

doi: 10.1371/journal.pntd.0009661. eCollection 2021 Sep.

A framework for scabies control

Daniel Engelman^{1

2

3}, Michael Marks^{4

5}, Andrew C Steer^{1

2

3}, Abate Beshah⁶, Gautam Biswas⁷, Olivier Chosidow^{8

9}, Luc E Coffeng¹⁰, Belen Lardizabal Dofitas^{11

12}, Wendemagegn Enbiale^{13

14}, Mosoka Fallah^{15

16}, Elkhan Gasimov¹⁷, Adrian Hopkins¹⁸, Julie Jacobson¹⁹, John M Kaldor²⁰, Fatimata Ly^{21

22}, Charles D Mackenzie²³, Jodie McVernon^{24

25

26}, Matthew Parnaby^{1

2}, Merelesita Rainima-Qaniuci²⁷, Oliver Sokana²⁸, Dieudonne Sankara⁷, Rie Yotsu^{29

30

31}, Aya Yajima³², Paul T Cantey^{33

34}

Affiliations

¹ Tropical Diseases, Murdoch Children's Research Institute, Melbourne, Australia.
² Melbourne Children's Global Health, Royal Children's Hospital, Melbourne, Australia.
³ Department of Paediatrics, University of Melbourne, Melbourne, Australia.
⁴ Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
⁵ Hospital for Tropical Diseases, London, United Kingdom.
⁶ Communicable Diseases, Neglected Tropical Diseases, WHO Regional Office for Africa, Brazzaville, Congo.
⁷ Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
⁸ Faculté de Santé de Créteil et Service de Dermatologie, APHP, Hôpital Henri-Mondor, Université Paris-Est, Créteil, France.
⁹ Research Group Dynamic, EA7380, Faculté de Santé de Créteil, Ecole Nationale Vétérinaire d'Alfort, USC ANSES, Université Paris-Est Créteil, Créteil, France.
¹⁰ Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
¹¹ College of Medicine, University of the Philippines, Manila, Philippines.
¹² Philippine Leprosy Mission, Inc., Manila, Philippines.
¹³ Department of Dermatovenerology, Bahir Dar University, Medicine and Health Science College, Addis Ababa, Ethiopia.
¹⁴ Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
¹⁵ University of Liberia, Monrovia, Liberia.
¹⁶ Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
¹⁷ Division of Country Health Programmes, Malaria, Neglected Tropical Diseases and Other Vector-borne Diseases, WHO Regional Office for Europe, Copenhagen, Denmark.
¹⁸ Independent Consultant, United Kingdom.
¹⁹ Bridges to Development, Seattle, Washington, United States of America.
²⁰ Public Health Interventions Research Group, Kirby Institute University of New South Wales, Sydney, Australia.
²¹ Dermatology Unit, EPS Institut d'Hygiéne Sociale de Dakar, Dakar, Senegal.
²² University Cheikh Anta Diop of Dakar, Dakar, Senegal.
²³ Task Force for Global Health, Decatur, Georgia, United States of America.
²⁴ Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
²⁵ Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
²⁶ Infection Modelling, Murdoch Children's Research Institute, Melbourne, Australia.
²⁷ Pacific Health Security & Communicable Diseases, Division of Pacific Technical Support, WHO, Suva, Fiji.
²⁸ Ministry of Health, Honiara, Solomon Islands.
²⁹ Tulane School of Public Health and Tropical Medicine, New Orleans, United States of America.
³⁰ School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
³¹ Department of Dermatology, National Center for Global Health and Medicine, Tokyo, Japan.
³² Division of Communicable Diseases, Medicines, Vaccines and Pharmaceuticals, WHO Regional Office for the Western Pacific, Manila, Philippines.
³³ Division of Parasitic Diseases and Malaria, US Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
³⁴ Former Medical Officer, Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.

PMID: 34473725
PMCID: PMC8412357
DOI: 10.1371/journal.pntd.0009661

A framework for scabies control

Daniel Engelman et al. PLoS Negl Trop Dis. 2021.

. 2021 Sep 2;15(9):e0009661.

doi: 10.1371/journal.pntd.0009661. eCollection 2021 Sep.

Authors

Affiliations

¹ Tropical Diseases, Murdoch Children's Research Institute, Melbourne, Australia.
² Melbourne Children's Global Health, Royal Children's Hospital, Melbourne, Australia.
³ Department of Paediatrics, University of Melbourne, Melbourne, Australia.
⁴ Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
⁵ Hospital for Tropical Diseases, London, United Kingdom.
⁶ Communicable Diseases, Neglected Tropical Diseases, WHO Regional Office for Africa, Brazzaville, Congo.
⁷ Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
⁸ Faculté de Santé de Créteil et Service de Dermatologie, APHP, Hôpital Henri-Mondor, Université Paris-Est, Créteil, France.
⁹ Research Group Dynamic, EA7380, Faculté de Santé de Créteil, Ecole Nationale Vétérinaire d'Alfort, USC ANSES, Université Paris-Est Créteil, Créteil, France.
¹⁰ Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
¹¹ College of Medicine, University of the Philippines, Manila, Philippines.
¹² Philippine Leprosy Mission, Inc., Manila, Philippines.
¹³ Department of Dermatovenerology, Bahir Dar University, Medicine and Health Science College, Addis Ababa, Ethiopia.
¹⁴ Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
¹⁵ University of Liberia, Monrovia, Liberia.
¹⁶ Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
¹⁷ Division of Country Health Programmes, Malaria, Neglected Tropical Diseases and Other Vector-borne Diseases, WHO Regional Office for Europe, Copenhagen, Denmark.
¹⁸ Independent Consultant, United Kingdom.
¹⁹ Bridges to Development, Seattle, Washington, United States of America.
²⁰ Public Health Interventions Research Group, Kirby Institute University of New South Wales, Sydney, Australia.
²¹ Dermatology Unit, EPS Institut d'Hygiéne Sociale de Dakar, Dakar, Senegal.
²² University Cheikh Anta Diop of Dakar, Dakar, Senegal.
²³ Task Force for Global Health, Decatur, Georgia, United States of America.
²⁴ Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
²⁵ Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
²⁶ Infection Modelling, Murdoch Children's Research Institute, Melbourne, Australia.
²⁷ Pacific Health Security & Communicable Diseases, Division of Pacific Technical Support, WHO, Suva, Fiji.
²⁸ Ministry of Health, Honiara, Solomon Islands.
²⁹ Tulane School of Public Health and Tropical Medicine, New Orleans, United States of America.
³⁰ School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
³¹ Department of Dermatology, National Center for Global Health and Medicine, Tokyo, Japan.
³² Division of Communicable Diseases, Medicines, Vaccines and Pharmaceuticals, WHO Regional Office for the Western Pacific, Manila, Philippines.
³³ Division of Parasitic Diseases and Malaria, US Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
³⁴ Former Medical Officer, Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.

PMID: 34473725
PMCID: PMC8412357
DOI: 10.1371/journal.pntd.0009661

Abstract

Scabies is a neglected tropical disease (NTD) that causes a significant health burden, particularly in disadvantaged communities and where there is overcrowding. There is emerging evidence that ivermectin-based mass drug administration (MDA) can reduce the prevalence of scabies in some settings, but evidence remains limited, and there are no formal guidelines to inform control efforts. An informal World Health Organization (WHO) consultation was organized to find agreement on strategies for global control. The consultation resulted in a framework for scabies control and recommendations for mapping of disease burden, delivery of interventions, and establishing monitoring and evaluation. Key operational research priorities were identified. This framework will allow countries to set control targets for scabies as part of national NTD strategic plans and develop control strategies using MDA for high-prevalence regions and outbreak situations. As further evidence and experience are collected and strategies are refined over time, formal guidelines can be developed. The control of scabies and the reduction of the health burden of scabies and associated conditions will be vital to achieving the targets set in WHO Roadmap for NTDs for 2021 to 2030 and the Sustainable Development Goals.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

**Fig 1. Overview of framework for scabies control.**
MDA, mass drug administration.

See this image and copyright information in PMC

References

1. World Health Organization. WHO informal consultation on a framework for scabies control: World Health Organization Regional Office for the Western Pacific: Manila, Philippines, 19–21 February 2019: meeting report. Geneva: World Health Organization; 2020.
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A framework for scabies control

Affiliations

A framework for scabies control

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

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Grants and funding

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Research Materials