Management of infectious complications associated with coronavirus infection in severe patients admitted to ICU
- PMID: 34475008
- PMCID: PMC8382590
- DOI: 10.1016/j.medine.2021.08.013
Management of infectious complications associated with coronavirus infection in severe patients admitted to ICU
Abstract
Infections have become one of the main complications of patients with severe SARS-CoV-2 pneumonia admitted in ICU. Poor immune status, frequent development of organic failure requiring invasive supportive treatments, and prolonged ICU length of stay in saturated structural areas of patients are risk factors for infection development. The Working Group on Infectious Diseases and Sepsis GTEIS of the Spanish Society of Intensive Medicine and Coronary Units SEMICYUC emphasizes the importance of infection prevention measures related to health care, the detection and early treatment of major infections in the patient with SARS-CoV-2 infections. Bacterial co-infection, respiratory infections related to mechanical ventilation, catheter-related bacteremia, device-associated urinary tract infection and opportunistic infections are review in the document.
Las infecciones se han convertido en una de las principales complicaciones de los pacientes con neumonía grave por SARS-CoV-2 que ingresan en UCI. El deficiente estado inmunitario, el desarrollo frecuente de fracaso orgánico con necesidad de tratamientos de soporte invasivos y las estancias prolongadas en áreas estructurales en gran medida saturadas de enfermos son factores de riesgo para el desarrollo de infecciones. El Grupo de Trabajo de Enfermedades Infecciosas y Sepsis GTEIS de la Sociedad Española de Medicina Intensiva y Unidades Coronarias SEMICYUC enfatiza la importancia de las medidas de prevención de infecciones relacionadas con los cuidados sanitarios, y de la detección y tratamiento precoz de las principales infecciones en el paciente con infección por SARS-CoV-2. La coinfección bacteriana, las infecciones respiratorias relacionadas con la ventilación mecánica, bacteriemia relacionada con el catéter, infección del tracto urinario asociado a dispositivo e infecciones oportunistas son desarrolladas.
Keywords: Infecciones oportunistas; Infection prevention; Neumonía; Nosocomial; Opportunistic infections; Pneumonia; Prevención infecciones; SARS-CoV-2.
Copyright © 2021 Elsevier España, S.L.U. and SEMICYUC. All rights reserved.
Similar articles
-
Management of infectious complications associated with coronavirus infection in severe patients admitted to ICU.Med Intensiva (Engl Ed). 2021 Apr 30:S0210-5691(21)00081-4. doi: 10.1016/j.medin.2021.04.007. Online ahead of print. Med Intensiva (Engl Ed). 2021. PMID: 34092423 English, Spanish.
-
[Management of infectious complications associated with coronavirus infection in severe patients admitted to ICU].Med Intensiva. 2021 Nov;45(8):485-500. doi: 10.1016/j.medin.2021.04.007. Epub 2021 Apr 30. Med Intensiva. 2021. PMID: 33994616 Free PMC article. Spanish.
-
Intensive care for seriously ill patients affected by novel coronavirus sars - CoV - 2: Experience of the Crema Hospital, Italy.Am J Emerg Med. 2021 Jul;45:156-161. doi: 10.1016/j.ajem.2020.08.005. Epub 2020 Aug 16. Am J Emerg Med. 2021. PMID: 33046317 Free PMC article.
-
Clinical Characteristics and Morbidity Associated With Coronavirus Disease 2019 in a Series of Patients in Metropolitan Detroit.JAMA Netw Open. 2020 Jun 1;3(6):e2012270. doi: 10.1001/jamanetworkopen.2020.12270. JAMA Netw Open. 2020. PMID: 32543702 Free PMC article. Review.
-
Global Impact of Coronavirus Disease 2019 Infection Requiring Admission to the ICU: A Systematic Review and Meta-analysis.Chest. 2021 Feb;159(2):524-536. doi: 10.1016/j.chest.2020.10.014. Epub 2020 Oct 15. Chest. 2021. PMID: 33069725 Free PMC article.
Cited by
-
Low Levels of Granulocytic Myeloid-Derived Suppressor Cells May Be a Good Marker of Survival in the Follow-Up of Patients With Severe COVID-19.Front Immunol. 2022 Jan 28;12:801410. doi: 10.3389/fimmu.2021.801410. eCollection 2021. Front Immunol. 2022. PMID: 35154077 Free PMC article.
-
Major alteration of lung microbiome and the host responses in critically ill COVID-19 patients with high viral load.Sci Rep. 2024 Nov 12;14(1):27637. doi: 10.1038/s41598-024-78992-1. Sci Rep. 2024. PMID: 39532981 Free PMC article.
-
Major alteration of Lung Microbiome and the Host Reaction in critically ill COVID-19 Patients with high viral load.Res Sq [Preprint]. 2024 Mar 8:rs.3.rs-3952944. doi: 10.21203/rs.3.rs-3952944/v1. Res Sq. 2024. Update in: Sci Rep. 2024 Nov 12;14(1):27637. doi: 10.1038/s41598-024-78992-1. PMID: 38496464 Free PMC article. Updated. Preprint.
-
Monocytic HLA-DR Expression in Immune Responses of Acute Pancreatitis and COVID-19.Int J Mol Sci. 2023 Feb 7;24(4):3246. doi: 10.3390/ijms24043246. Int J Mol Sci. 2023. PMID: 36834656 Free PMC article. Review.
-
Microbiological diagnosis of pulmonary invasive aspergillosis in critically ill patients with severe SARS-CoV-2 pneumonia: a bronchoalveolar study.Ann Clin Microbiol Antimicrob. 2023 Oct 10;22(1):90. doi: 10.1186/s12941-023-00626-7. Ann Clin Microbiol Antimicrob. 2023. PMID: 37817167 Free PMC article.
References
-
- Rodríguez A., Ruiz-Botella M., Martín-Loeches I., Jimenez Herrera M., Solé-Violan J., Gómez J., et al. COVID-19 SEMICYUC Working Group. Deploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain. Crit Care. 2021;25:63. doi: 10.1186/s13054-021-03487-8. PMID: 33588914; PMCID: PMC7883885. - DOI - PMC - PubMed
-
- Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (SEMICYUC), Grupo de Trabajo de Enfermedades Infecciosas y Sepsis (GTEIS) 2020. Estudio Nacional de Vigilancia de Infección Nosocomial. ENVIN-COVID. Available from: https://hws.vhebron.net/envin-helics/ [Accessed 13 April 2021]
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous