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Comment
. 2021 Oct:206:137-138.
doi: 10.1016/j.thromres.2021.08.018. Epub 2021 Aug 28.

Thrombosis post COVID-19 vaccinations: Potential link to ACE pathways

Rinkoo Dalan  1 , Bernhard O Boehm  2
Affiliations
Comment

Thrombosis post COVID-19 vaccinations: Potential link to ACE pathways

Rinkoo Dalan et al. Thromb Res. 2021 Oct.
No abstract available

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Figure showing the likely mechanisms of increased susceptibility to thrombosis: 1. ACE2 receptor mutation leading to increased sensitivity to interaction with spike protein and a decrease in AgII-Mas pathway with unopposed AgII-AT1-4R receptor signaling; 2. ACE receptor mutation leading to higher propensity towards activation of the AgII pathway relative to Mas receptor and downstream activation of AgII Type 1 (AT1R), Type 2(AT2R) and Type 4 receptors (AT4R) leading to higher propensity for macrovascular (AT1R) and microvascular thrombosis (AT2 & AT4).
See this image and copyright information in PMC

Comment on

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