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. 2021 Dec;85(6):650-659.
doi: 10.1111/cod.13966. Epub 2021 Sep 24.

Facial contact dermatitis caused by cosmetic-relevant allergens

Maria A Bruusgaard-Mouritsen  1 , Lene H Garvey  2   3 , Jeanne D Johansen  1
Affiliations

Facial contact dermatitis caused by cosmetic-relevant allergens

Maria A Bruusgaard-Mouritsen et al. Contact Dermatitis. 2021 Dec.

Abstract

Background: Facial allergic contact dermatitis caused by cosmetic products is common. New allergens in cosmetics continuously emerge.

Objectives: To investigate characteristics of patients with facial dermatitis (FD) between 2010 and 2019 including patch test results from cosmetic-related allergens and a new test series with cosmetic-relevant natural ingredients (CRNIs).

Methods: This is a retrospective study analysing demographics, clinical characteristics according to MOAHLFA index (male; occupation; atopic dermatitis; hand; leg; face; age ≥ 40 years), and patch test results to 27 cosmetic-relevant allergens in FD patients. A prospective study evaluating a screening test series with CRNIs in consecutive FD patients for 1 year was also conducted. These patients received a questionnaire for collecting extra characteristics (eg, concerning quality of life).

Results: Of 8740 tested patients, 2292 (26.2%) had FD. Of these, 30.6% had cosmetic-induced FD. The most common cosmetic-related allergens were fragrances and preservatives. The most common patch test-positive CRNIs were hydroperoxides of limonene and linalool, and propolis. Potato and peanut were rare, but the most common prick test-positive CRNIs, however, without any relation to the use of cosmetic products. FD affected nearly all patients' quality of life and caused limitations to their daily life.

Conclusions: Updated management and quick diagnosis of FD is important to avoid negative impact on patients' quality of life.

Keywords: cosmetic products; facial dermatitis; natural ingredients; patch test; skin prick test.

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References

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