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. 2022 Jan;3(1):227-232.
doi: 10.1002/nano.202100069. Epub 2021 Jun 1.

Colloidal dispersion of poly(ionic liquid)/Cu composite particles for protective surface coating against SAR-CoV-2

Atefeh Khorsand Kheirabad  1 , Xuefeng Pan  2 , Siwen Long  3 , Zdravko Kochovski  2 , Shiqi Zhou  1 , Yan Lu  2   4 , Gerald McInerney  3 , Jiayin Yuan  1
Affiliations

Colloidal dispersion of poly(ionic liquid)/Cu composite particles for protective surface coating against SAR-CoV-2

Atefeh Khorsand Kheirabad et al. Nano Sel. 2022 Jan.

Abstract

Herein, we report a waterproof anti-SARS-CoV-2 protective film prepared by spray-coating of an aqueous colloidal dispersion of poly(ionic liquid)/copper (PIL/Cu) composite nanoparticles onto a substrate. The PIL dispersion was prepared by suspension polymerization of 3-dodecyl-1-vinylimdiazolium bromide in water at 70°C. The copper acetate salt was added into the PIL nanoparticle dispersion and in situ reduced into copper nanoparticles anchoring onto the PIL nanoparticles. Despite being waterborne, the PIL in bulk is intrinsically insoluble in water and the formed coating is stable in water. The formed surface coating by PIL/copper composite nanoparticles was able to deactivate SARS-CoV-2 virions by 90.0% in 30 minutes and thus may effectively prevent the spread of SARS-CoV-2 through surface contact. This method may provide waterborne dispersions for a broad range of antivirus protective surface coatings for both outdoor and indoor applications.

Keywords: SARS‐CoV‐2; antivirus coating; colloidal dispersion; copper nanoparticle; poly(ionic liquid).

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Figures

FIGURE 1
FIGURE 1
Schematic representation of the surface spray coating of a glass substrate by an aqueous colloidal dispersion of PIL/Cu composite nanoparticles
FIGURE 2
FIGURE 2
A), Cryo‐TEM overview image of the pristine PIL nanoparticles dispersed in aqueous solution. B), The enlarged view (The inset on the bottom left is a cartoon showing the inner structure of a single PIL nanoparticle)
FIGURE 3
FIGURE 3
A), SEM image of the PIL/Cu composite nanoparticles on a glass substrate. B), Cryo‐TEM image of PIL/Cu nanoparticles dispersed in aqueous media. C), XRD patterns of PIL and the PIL/Cu composite nanoparticles. D), TGA curve of the PIL/Cu composite nanoparticles under air from room temperature to 900 °C
FIGURE 4
FIGURE 4
A, B), Water contact angle measurements of glass substrates coated with PIL nanoparticles, and the PIL/Cu composite nanoparticles, respectively. C), Characterization of antiviral activity of glass slides coated with PIL nanoparticles and the composite of the PIL/Cu nanoparticles against SARS‐CoV‐2 virions at various times
See this image and copyright information in PMC

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