Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Oct 4;153(10):e202112988.
doi: 10.1085/jgp.202112988. Epub 2021 Sep 7.

How do batrachotoxin-bearing frogs and birds avoid self intoxication?

Roberto Márquez  1   2
Affiliations
Comment

How do batrachotoxin-bearing frogs and birds avoid self intoxication?

Roberto Márquez. J Gen Physiol. .

Abstract

Abderemane-Ali et al. investigated the mechanisms underlying self-resistance in poison dart frogs and poison birds.

PubMed Disclaimer

Comment on

References

    1. Abderemane-Ali, F., Rossen N.D., Kobiela M.E., Craig R.A., Garrison C.E., Chen Z., Colleran C.M., O’Connell L.A., Du Bois J., Dumbacher J.P., and Minor D.L.. 2021. Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on “toxin sponge” proteins. J. Gen. Physiol. 153:e202112872. 10.1085/jgp.202112872 - DOI - PMC - PubMed
    1. Albuquerque, E.X., Warnick J.E., Sansone F.M., and Daly J.. 1973. The pharmacology of batrachotoxin. V. A comparative study of membrane properties and the effect of batrachotoxin on sartorius muscles of the frogs Phyllobates aurotaenia and Rana pipiens J. Pharmacol. Exp. Ther. 184:315–329 - PubMed
    1. Berenbaum, M.R. 1995. The chemistry of defense: theory and practice. Proc. Natl. Acad. Sci. USA. 92:2–8. 10.1073/pnas.92.1.2 - DOI - PMC - PubMed
    1. Bisset, N.G. 1989. Arrow and dart poisons. J. Ethnopharmacol. 25:1–41. 10.1016/0378-8741(89)90043-3 - DOI - PubMed
    1. Bosmans, F., Maertens C., Verdonck F., and Tytgat J.. 2004. The poison Dart frog’s batrachotoxin modulates Nav1.8. FEBS Lett. 577:245–248. 10.1016/j.febslet.2004.10.017 - DOI - PubMed

Publication types

LinkOut - more resources