How do batrachotoxin-bearing frogs and birds avoid self intoxication?
- PMID: 34491263
- PMCID: PMC8421260
- DOI: 10.1085/jgp.202112988
How do batrachotoxin-bearing frogs and birds avoid self intoxication?
Abstract
Abderemane-Ali et al. investigated the mechanisms underlying self-resistance in poison dart frogs and poison birds.
Comment on
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Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on "toxin sponge" proteins.J Gen Physiol. 2021 Sep 6;153(9):e202112872. doi: 10.1085/jgp.202112872. Epub 2021 Aug 5. J Gen Physiol. 2021. PMID: 34351379 Free PMC article.
References
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- Abderemane-Ali, F., Rossen N.D., Kobiela M.E., Craig R.A., Garrison C.E., Chen Z., Colleran C.M., O’Connell L.A., Du Bois J., Dumbacher J.P., and Minor D.L.. 2021. Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on “toxin sponge” proteins. J. Gen. Physiol. 153:e202112872. 10.1085/jgp.202112872 - DOI - PMC - PubMed
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- Albuquerque, E.X., Warnick J.E., Sansone F.M., and Daly J.. 1973. The pharmacology of batrachotoxin. V. A comparative study of membrane properties and the effect of batrachotoxin on sartorius muscles of the frogs Phyllobates aurotaenia and Rana pipiens J. Pharmacol. Exp. Ther. 184:315–329 - PubMed
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