Alveolar macrophages and epithelial cells: The art of living together
- PMID: 34491265
- PMCID: PMC8421265
- DOI: 10.1084/jem.20211583
Alveolar macrophages and epithelial cells: The art of living together
Abstract
In this issue of JEM, Gschwend et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20210745) reveal the indispensable role of alveolar epithelial cells type 2 in controlling the density of alveolar macrophages. This study highlights the intricate crosstalk that lung stroma and macrophages undergo to maintain homeostasis.
© 2021 Clements and Idoyaga.
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Comment on
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Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth.J Exp Med. 2021 Oct 4;218(10):e20210745. doi: 10.1084/jem.20210745. Epub 2021 Aug 25. J Exp Med. 2021. PMID: 34431978 Free PMC article.