Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep;9(1):e002267.
doi: 10.1136/bmjdrc-2021-002267.

Screening attendance, prevalence and severity of diabetic retinopathy (DR) in a cohort of patients with diabetes mellitus secondary to chronic pancreatitis (DMsCP) in Northern Ireland

Catherine Jamison  1 , Tunde Peto  1 , Nicola Quinn  1 , Rossella D'Aloisio  2 , Laura Nicole Cushley  1 , Philip C Johnston  3   4
Affiliations

Screening attendance, prevalence and severity of diabetic retinopathy (DR) in a cohort of patients with diabetes mellitus secondary to chronic pancreatitis (DMsCP) in Northern Ireland

Catherine Jamison et al. BMJ Open Diabetes Res Care. 2021 Sep.

Abstract

Introduction: This study investigated Northern Ireland Diabetic Eye Screening Programme (NIDESP) attendance and diabetic retinopathy (DR) prevalence/severity in patients with diabetes mellitus secondary to chronic pancreatitis (PwDMsCP).

Research design and methods: Medical/NIDESP records for all PwDMsCP attending the pancreatic diabetes clinic were analyzed in 2017 (n=78) and 2019 (n=94).

Results: Between 2017 and 2019, those without DR decreased (76% to 63%); mild non-proliferative DR (NPDR), severe NPDR and PDR were found in 30%, 2% and 5%, respectively (previously 18%, 4%, 2%); diabetic maculopathy (DMac) was present in 12% (previously 10%). There was no significant difference between worst-eye DR/DMac grade and HbA1c, gender, body mass index, pancreatitis etiology and screening attendance (p>0.05). Patients with proliferative DR had longer diabetes and pancreatitis duration than DR-free patients (both p=0.001).

Conclusions: DR prevalence was similar in PwDMsCP and patients with type 2 diabetes of similar disease duration. This work demonstrates the importance of reaching all patients for establishing DR severity reliably and to provide accessible, equitable care to PwDMsCP.

Keywords: diabetes complications; diabetic retinopathy; eye diseases; pancreas.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

References

    1. Ewald N, Kaufmann C, Raspe A, et al. . Prevalence of diabetes mellitus secondary to pancreatic diseases (type 3C). Diabetes Metab Res Rev 2012;28:338–42. 10.1002/dmrr.2260 - DOI - PubMed
    1. Makuc J. Management of pancreatogenic diabetes: challenges and solutions. Diabetes Metab Syndr Obes 2016;9:311–5. 10.2147/DMSO.S99701 - DOI - PMC - PubMed
    1. Ewald N, Hardt PD. Diagnosis and treatment of diabetes mellitus in chronic pancreatitis. World J Gastroenterol 2013;19:7276–81. 10.3748/wjg.v19.i42.7276 - DOI - PMC - PubMed
    1. Harding S, Greenwood R, Aldington S, et al. . Grading and disease management in national screening for diabetic retinopathy in England and Wales. Diabet Med 2003;20:965–71. 10.1111/j.1464-5491.2003.01077.x - DOI - PubMed
    1. Gullo L, Parenti M, Monti L, et al. . Diabetic retinopathy in chronic pancreatitis. Gastroenterology 1990;98:1577–81. 10.1016/0016-5085(90)91093-L - DOI - PubMed

MeSH terms