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. 2022:48:1258-1264.
doi: 10.1016/j.matpr.2021.08.265. Epub 2021 Sep 3.

Therapeutic approaches in COVID-19 followed before arrival of any vaccine

Vasundhra Sharma  1 , Atul Pratap Singh  1 , Ashish Pratap Singh  2
Affiliations

Therapeutic approaches in COVID-19 followed before arrival of any vaccine

Vasundhra Sharma et al. Mater Today Proc. 2022.

Abstract

In present times covid-19 is spreading and is showing very destructive effects. It does not only affected the physical health but mental health as well as the economy of the major affected countries. Corona viruses are group of related RNA viruses. The first case of this virus was observed in China and then this virus got spread in the many countries and different strategies were made to stop the spread of this virus. Since no particular vaccine was available to cure this so different strategies were made. Due to the emergence of pandemic diseases, drug development and control strategies have been re-examined. One of the most important factors that scientists have to consider is the effectiveness of their drugs. This virus causes the respiratory tract infections which can range from mild to lethal. COVID-19 is a major cause of death in advanced countries. It is due to the absence of any particular vaccine that can effectively treat this condition. So in this review we will discuss about the therapeutic approaches followed to combat this deadly virus. Ayurveda, nitric oxide, nanoparticles and enzymes played a very important role in boosting the immunity and treatment of corona. Many herbs and some tips of using a combination of herbs proved to be very efficient while facing problems in breathing. Giving the dose of nitric oxide at some particular level and chloroquine the drug showed the antiviral activity against the virus. Developing methods to identify and contain COVID-19 is essential to successfully manage the virus. Various strains of the SARS-COV-2 were detected and were found more dangerous. The therapeutic approaches followed actually were efficient and can be used to combat the other variants also. This review focuses on the latest developments in the field of therapeutics and the strategies which were followed before any vaccine.

Keywords: MERS (Middle East respiratory disorder Covid); Nitric oxide (NO); SARS-CoV (serious intense respiratory condition Covid).

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Structure of Cov-19.
Fig. 2
Fig. 2
Attack of virus on body.
Fig. 3
Fig. 3
Mechanism of transmembrane transport of nutrients.
Fig. 4
Fig. 4
Structure of Chloroquine.
Fig. 5
Fig. 5
Structure of hydrochloroquine.
See this image and copyright information in PMC

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References

    1. WHO, https://www.who.int/csr/don/14-january-2020-novel-coronavirus-thailand/en/
    1. C. Rothe, M. Schunk, P. Sothmann, et al., Transmission of 2019-nCoV infection from an asymptomatic contact in Germany, 2020. - PMC - PubMed
    1. Q. Li, X. Guan, P. Wu, et al., Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia, 2020. - PMC - PubMed
    1. A.R. Fehr, S. Perlman, Coronaviruses: an overview of their replication and pathogenesis, Methods Mol. Biol. (2015). - PMC - PubMed
    1. R. Dijkman, L. van der Hoek, Human coronaviruses 229E and NL63: close yet still so far, J. Formos. Med. Assoc. (2009). - PMC - PubMed

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