Late Coronary Aneurysm Formation after Kawasaki Disease: a Review of Mechanistic and Clinical Aspects
- PMID: 34494409
- PMCID: PMC8484996
- DOI: 10.4070/kcj.2021.0098
Late Coronary Aneurysm Formation after Kawasaki Disease: a Review of Mechanistic and Clinical Aspects
Abstract
In patients with Kawasaki disease (KD), evolution of coronary artery aneurysms (CAAs) generally emerges within the first few weeks after disease onset. However, CAA formation in these patients might occasionally arise as a late-onset phenomenon after a long latent period. Characteristically, late CAAs manifest as new-onset vascular pathologies or expansion of long-stable CAAs on coronary imaging modalities, and might have diverse mechanistic and clinical implications. Accordingly, the present paper aims to focus on late CAA formation and its implications in the setting of KD.
Keywords: Aneurysm; Coronary artery; Kawasaki disease.
Copyright © 2021. The Korean Society of Cardiology.
Conflict of interest statement
The authors have no financial conflicts of interest.
Figures
References
-
- McCrindle BW, Rowley AH, Newburger JW, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association. Circulation. 2017;135:e927–e999. - PubMed
-
- Pacheco DA, Miller CR, Boor PJ, Mambo NC. Incomplete Kawasaki disease with development of fatal coronary artery thrombosis in a 13-year-old male. Cardiovasc Pathol. 2019;42:54–58. - PubMed
-
- Pucci A, Martino S, Celeste A, et al. Angiogenesis, tumor necrosis factor-alpha and procoagulant factors in coronary artery giant aneurysm of a fatal infantile Kawasaki disease. Cardiovasc Pathol. 2008;17:186–189. - PubMed
-
- Lee CH, Kim U. Coronary artery aneurysm in Kawasaki disease: from multimodality imaging. Coron Artery Dis. 2020;31:193–194. - PubMed