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. 2021:1325:61-102.
doi: 10.1007/978-3-030-70115-4_3.

Glycosphingolipids

Elena Chiricozzi  1 , Massimo Aureli  1 , Laura Mauri  1 , Erika Di Biase  1 , Giulia Lunghi  1 , Maria Fazzari  1 , Manuela Valsecchi  1 , Emma Veronica Carsana  1 , Nicoletta Loberto  1 , Alessandro Prinetti  1 , Sandro Sonnino  2
Affiliations

Glycosphingolipids

Elena Chiricozzi et al. Adv Exp Med Biol. 2021.

Abstract

Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology.In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this, their property to modulate positively in health and negatively in disease, the cell signaling and cell biology.

Keywords: Cancer; Ceramide; Glycosphingolipids; Neurodegeneration; Neuroprotection; Sphingosine.

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