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Review
. 2021 Aug 14;27(30):5037-5046.
doi: 10.3748/wjg.v27.i30.5037.

Role of exercise in preventing and restoring gut dysbiosis in patients with inflammatory bowel diseases: A review

Tilemachos Koutouratsas  1 , Anastassios Philippou  2 , George Kolios  3 , Michael Koutsilieris  2 , Maria Gazouli  4
Affiliations
Review

Role of exercise in preventing and restoring gut dysbiosis in patients with inflammatory bowel diseases: A review

Tilemachos Koutouratsas et al. World J Gastroenterol. .

Abstract

Inflammatory bowel diseases (IBD) include a spectrum of chronic inflammatory disorders of the gastrointestinal tract whose pathogenesis is yet to be elucidated. The intestinal microbiome has been studied as a causal component, with certain microbiotic alterations having been observed in subtypes of IBD. Physical exercise is a modulator of the intestinal microbiome, causing shifts in its composition that are partially corrective of those observed in IBD; furthermore, physical exercise may be beneficial in patients with certain IBD subtypes. This review studies the effects of physical exercise on the human gut microbiome while investigating pathophysiologic mechanisms that could explain physical activity's clinical effects on patients with IBD.

Keywords: Crohn’s disease; Exercise; Inflammatory bowel disease; Microbiome; Pouchitis; Ulcerative colitis.

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Conflict of interest statement

Conflict-of-interest statement: Authors have nothing to disclose.

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