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Review
. 2021 Aug 28:2021:4572743.
doi: 10.1155/2021/4572743. eCollection 2021.

Prevalence of Chronic Kidney Diseases in Patients with Diabetes Mellitus in the Middle East: A Systematic Review and Meta-Analysis

Abdallah Y Naser  1 , Hassan Alwafi  2 , Basil Alotaibi  3 , Emad Salawati  4 , Mohammed Samannodi  2 , Zahra Alsairafi  5 , Abeer F R Alanazi  6 , Mohammad S Dairi  2
Affiliations
Review

Prevalence of Chronic Kidney Diseases in Patients with Diabetes Mellitus in the Middle East: A Systematic Review and Meta-Analysis

Abdallah Y Naser et al. Int J Endocrinol. .

Abstract

Aims: The prevalence of CKD in patients with diabetes mellitus in the Middle East region is unknown. Therefore, we aimed to understand the pooled prevalence of CKD in patients with diabetes mellitus in the Middle East region.

Methods: PubMed, Embase, and Cochrane databases were searched for relevant studies up to October 2020. The search strategy was conducted using both keywords and MeSH terms. Randomised controlled trials (RCTs) and observational studies that included patients from all age groups and any study design that reported on the prevalence of CKD in patients with diabetes mellitus were included. The pooled estimate for the prevalence of CKD in patients with diabetes was calculated using random-effect models with 95% confidence intervals (CIs).

Results: A total of 489 citations were identified, of which only nine studies matched our inclusion criteria and were included in the meta-analysis. All of the studies used an observational study design covering a total of 59,395 patients with type 2 diabetes mellitus. The pooled estimate of the prevalence of CKD in patients with diabetes mellitus was 28.96% (95% CI: 19.80-38.11).

Conclusions: A high prevalence of CKD in patients with diabetes mellitus in the Middle East region was found. Further epidemiological studies are warranted in this area to have a better estimate of the prevalence of CKD among DM in the Middle East region.

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Conflict of interest statement

All authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
PRISMA flow diagram showing the study selection process.
Figure 2
Figure 2
Forest plot showing the prevalence of CKD in T2DM patients.
Figure 3
Figure 3
Forest plot showing the prevalence of CKD in T2DM patients stratified by location.
Figure 4
Figure 4
Forest plot showing the prevalence of CKD in T2DM patients stratified by the data source.
Figure 5
Figure 5
Funnel plot showing evidence of publication bias.
See this image and copyright information in PMC

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