A national survey on prevalence of possible echocardiographic red flags of amyloid cardiomyopathy in consecutive patients undergoing routine echocardiography: study design and patients characterization - the first insight from the AC-TIVE Study

Marco Merlo¹, Aldostefano Porcari¹, Linda Pagura¹, Matteo Cameli², Giuseppe Vergaro³, Beatrice Musumeci⁴, Elena Biagini⁵, Marco Canepa^{6

7}, Lia Crotti^{8

9}, Massimo Imazio¹⁰, Cinzia Forleo¹¹, Francesco Cappelli¹², Stefano Favale¹¹, Gianluca Di Bella¹³, Franca Dore¹⁴, Carlo Mario Lombardi¹⁵, Rita Pavasini¹⁶, Valeria Rella⁸, Giuseppe Palmiero¹⁷, Martina Caiazza¹⁷, Miriam Albanese¹¹, Andrea Igoren Guaricci¹¹, Giovanna Branzi⁸, Angelo Giuseppe Caponetti⁵, Giulia Saturi⁵, Giovanni La Malfa⁶, Andrea Carlo Merlo⁶, Alessandro Andreis¹⁰, Francesco Bruno¹⁰, Francesca Longo¹, Enrico Sfriso¹, Luca Di Ienno¹⁶, Giuseppe De Carli², Elisa Giacomin², Valentina Spini³, Antonino Milidoni¹⁵, Giuseppe Limongelli¹⁷, Camillo Autore⁴, Iacopo Olivotto¹², Luigi Badano^{8

9}, Gianfranco Parati^{8

9}, Stefano Perlini^{18

19}, Marco Metra¹⁵, Michele Emdin³, Claudio Rapezzi^{20

21}, Gianfranco Sinagra¹

Affiliations

¹ Cardiovascular Department, Center for Diagnosis and Treatment of Cardiomyopathies, Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste, Via Valdoni 1, 34149 Trieste, Italy.
² Division of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Mario Bracci 16, 53100, Siena, Italy.
³ Division of Cardiology and Cardiovascular Medicine, Fondazione Toscana Gabriele Monasterio and Istituto di Scienze della Vita, Scuola Superiore Sant'Anna, Via Giuseppe Moruzzi 1, 56124, Pisa, Italy.
⁴ Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sapienza University, Via di Grottarossa 1035-39, 00189, Rome, Italy.
⁵ Department of Experimental, Diagnostic and Specialty Medicine, Cardiology Unit, IRCCS, University Sant'Orsola Hospital, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy.
⁶ Department of Internal Medicine, Cardiovascular Unit, University of Genova, Viale Benedetto XV 10, 16132, Genova, Italy.
⁷ Ospedale Policlinico San Martino IRCCS, Largo Rosanna Benzi 10, 16132, Genova, Italy.
⁸ Department of Cardiovascular, Neural and Metabolic Sciences, Cardiomyopathy Unit, Istituto Auxologico Italiano, Piazzale Brescia, 20, 20149, Milan, Italy.
⁹ Department of Medicine and Surgery, University Milano, Bicocca, Piazza dell'Ateneo Nuovo 1, 20126, Milan, Italy.
¹⁰ Division of Cardiology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, University of Turin, Corso Bramante 88, 10126, Turin, Italy.
¹¹ Department of Emergency and Organ Transplantation, Cardiology Unit, University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70124, Bari, Italy.
¹² Cardiomyopathy Unit, Careggi University Hospital, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
¹³ Department of Cardiology, University of Messina, Via Consolare Valeria 1, 98125, Messina, Italy.
¹⁴ Department of Nuclear Medicine, Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste, Strada di Fiume 447, 34129, Trieste, Italy.
¹⁵ Cardiology, Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Piazzale Spedali Civili 1, 25123, Brescia, Italy.
¹⁶ Cardiology Unit, Azienda Ospedaliero Universitaria di Ferrara, Cona, Via Aldo Moro 8, 44124, Ferrara, Italy.
¹⁷ Department of Translational Medical Sciences, Inherited and Rare Heart Disease, Vanvitelli Cardiology, University of Campania Luigi Vanvitelli, Piazza Luigi Miraglia 2, 80138, Napoli, Italy.
¹⁸ Emergency Department and Amyloid Research and Treatment Center, IRCCS Policlinico San Matteo Foundation, Viale Camillo Golgi 19, 27100, Pavia, Italy.
¹⁹ Department of Internal Medicine, University of Pavia, Via Aselli 43/45, 27100, Pavia, Italy.
²⁰ Cardiovascular Center, University of Ferrara, Via Savonarola 9, 44121, Ferrara, Italy.
²¹ Maria Cecilia Hospital, GVM Care & Research, Via Corriera, 1, 48033, Cotignola, Italy.

PMID: 34499711
DOI: 10.1093/eurjpc/zwab127

Free article

A national survey on prevalence of possible echocardiographic red flags of amyloid cardiomyopathy in consecutive patients undergoing routine echocardiography: study design and patients characterization - the first insight from the AC-TIVE Study

Marco Merlo et al. Eur J Prev Cardiol. 2022.

Free article

. 2022 May 5;29(5):e173-e177.

doi: 10.1093/eurjpc/zwab127.

Authors

Affiliations

¹ Cardiovascular Department, Center for Diagnosis and Treatment of Cardiomyopathies, Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste, Via Valdoni 1, 34149 Trieste, Italy.
² Division of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Mario Bracci 16, 53100, Siena, Italy.
³ Division of Cardiology and Cardiovascular Medicine, Fondazione Toscana Gabriele Monasterio and Istituto di Scienze della Vita, Scuola Superiore Sant'Anna, Via Giuseppe Moruzzi 1, 56124, Pisa, Italy.
⁴ Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sapienza University, Via di Grottarossa 1035-39, 00189, Rome, Italy.
⁵ Department of Experimental, Diagnostic and Specialty Medicine, Cardiology Unit, IRCCS, University Sant'Orsola Hospital, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy.
⁶ Department of Internal Medicine, Cardiovascular Unit, University of Genova, Viale Benedetto XV 10, 16132, Genova, Italy.
⁷ Ospedale Policlinico San Martino IRCCS, Largo Rosanna Benzi 10, 16132, Genova, Italy.
⁸ Department of Cardiovascular, Neural and Metabolic Sciences, Cardiomyopathy Unit, Istituto Auxologico Italiano, Piazzale Brescia, 20, 20149, Milan, Italy.
⁹ Department of Medicine and Surgery, University Milano, Bicocca, Piazza dell'Ateneo Nuovo 1, 20126, Milan, Italy.
¹⁰ Division of Cardiology, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, University of Turin, Corso Bramante 88, 10126, Turin, Italy.
¹¹ Department of Emergency and Organ Transplantation, Cardiology Unit, University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70124, Bari, Italy.
¹² Cardiomyopathy Unit, Careggi University Hospital, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
¹³ Department of Cardiology, University of Messina, Via Consolare Valeria 1, 98125, Messina, Italy.
¹⁴ Department of Nuclear Medicine, Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste, Strada di Fiume 447, 34129, Trieste, Italy.
¹⁵ Cardiology, Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Piazzale Spedali Civili 1, 25123, Brescia, Italy.
¹⁶ Cardiology Unit, Azienda Ospedaliero Universitaria di Ferrara, Cona, Via Aldo Moro 8, 44124, Ferrara, Italy.
¹⁷ Department of Translational Medical Sciences, Inherited and Rare Heart Disease, Vanvitelli Cardiology, University of Campania Luigi Vanvitelli, Piazza Luigi Miraglia 2, 80138, Napoli, Italy.
¹⁸ Emergency Department and Amyloid Research and Treatment Center, IRCCS Policlinico San Matteo Foundation, Viale Camillo Golgi 19, 27100, Pavia, Italy.
¹⁹ Department of Internal Medicine, University of Pavia, Via Aselli 43/45, 27100, Pavia, Italy.
²⁰ Cardiovascular Center, University of Ferrara, Via Savonarola 9, 44121, Ferrara, Italy.
²¹ Maria Cecilia Hospital, GVM Care & Research, Via Corriera, 1, 48033, Cotignola, Italy.

PMID: 34499711
DOI: 10.1093/eurjpc/zwab127

No abstract available

Keywords: Cardiac amyloidosis; Echocardiography; Epidemiology; Prevalence; Red-flags.

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A national survey on prevalence of possible echocardiographic red flags of amyloid cardiomyopathy in consecutive patients undergoing routine echocardiography: study design and patients characterization - the first insight from the AC-TIVE Study

Affiliations

A national survey on prevalence of possible echocardiographic red flags of amyloid cardiomyopathy in consecutive patients undergoing routine echocardiography: study design and patients characterization - the first insight from the AC-TIVE Study

Authors

Affiliations

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical