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Randomized Controlled Trial
. 2021 Aug 31;18(17):9205.
doi: 10.3390/ijerph18179205.

Effects of Intradialytic Exercise on Dialytic Parameters, Health-Related Quality of Life, and Depression Status in Hemodialysis Patients: A Randomized Controlled Trial

Chia-Huei Lin  1   2 , Yu-Juei Hsu  3   4 , Pi-Hsiu Hsu  5 , Yi-Ling Lee  6 , Chueh-Ho Lin  7   8 , Meei-Shyuan Lee  9 , Shang-Lin Chiang  4   10
Affiliations
Randomized Controlled Trial

Effects of Intradialytic Exercise on Dialytic Parameters, Health-Related Quality of Life, and Depression Status in Hemodialysis Patients: A Randomized Controlled Trial

Chia-Huei Lin et al. Int J Environ Res Public Health. .

Abstract

Exercise is fundamentally important in managing chronic diseases and improving health-related quality of life (HRQL). However, whether intradialytic exercise is safe through assessment of changes in dialytic parameters and has a positive impact on HRQL and depression status of hemodialysis patients requires further research with diverse racial and cultural populations to identify. This study aimed to evaluate the effects of intradialytic exercise on dialytic parameters, HRQL, and depression status in hemodialysis patients. A randomized controlled trial was conducted at a medical center in Northern Taiwan. Sixty-four hemodialysis patients were recruited using stratified random sampling. Participants were randomized into an experimental group (EG, n = 32) or a control group (CG, n = 32). The EG received a 12-week intradialytic exercise program while the CG maintained their usual lifestyles. Dialytic parameters, HRQL, and depression status were collected at baseline and at 12 weeks. The results indicated no differences in the dialytic parameters from the baseline between both groups. However, the EG had increased HRQL (ß = 22.6, p < 0.001) and reduced depression status (ß = -7.5, p = 0.02) at 12 weeks compared to the CG. Therefore, a 12-week intradialytic exercise regime is safe and effective in improving HRQL and reducing depression status for hemodialysis patients.

Keywords: depression status; exercise; health-related quality of life; hemodialysis; intradialytic exercise.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
CONSORT Diagram of Participants’ Flow Through the Trial.
See this image and copyright information in PMC

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