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Review
. 2021 Dec;8(6):5551-5554.
doi: 10.1002/ehf2.13565. Epub 2021 Sep 10.

The dominant left ventricular assist device: lessons from an era

Amit Alam  1   2 , Gregory P Milligan  1 , Timothy Gong  1   2
Affiliations
Review

The dominant left ventricular assist device: lessons from an era

Amit Alam et al. ESC Heart Fail. 2021 Dec.

Abstract

The production and distribution of the HeartWare ventricular assist device has come to an abrupt end, but with this end comes the opportunity to reflect upon lessons learned from its lifespan. Running counter to the standard of evidence-based practice, the era of the HeartWare ventricular assist device was marred with fragmented data in relation to its primary counterpart, the HeartMate III. This created an incomplete understanding of devices, limited individualized patient care, and effectively positioned providers to make inferences regarding device superiority. We briefly review pertinent literature on this topic among the most commonly implanted durable devices from the era, detail the inherent limitations of this data, and argue the necessity of randomized clinical trials among novel devices towards the optimization of patient care.

Keywords: Circulatory support; Heart failure; LVAD; Left ventricular assist device.

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Figures

Figure 1
Figure 1
HVAD vs. HM3 trial design. BTT, bridge to transplant; DT, destination therapy; HM3, HeartMate3; HVAD, HeartWare ventricular assist device; LVAD, Left ventricular assist device.
See this image and copyright information in PMC

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