Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Dec;22(12):1053-6.
doi: 10.1007/BF02536450.

Effects of eicosatetraynoic acid on membrane lipids of trout liver and intestine

Affiliations

Effects of eicosatetraynoic acid on membrane lipids of trout liver and intestine

X Pelletier et al. Lipids. 1987 Dec.

Abstract

After two months feeding either an (n-3) or an (n-6) fatty acid-rich diet, two groups of trout were switched to the (n-6) or the (n-3) fatty acid-rich diet, respectively. Half of each group was treated with 0.03% 5,8,11,14-eicosatetraynoic acid (ETYA) in the diet. Liver and intestinal brush border membrane lipids were analyzed. No effect was observed on their cholesterol content. ETYA induced an accumulation of 18:2(n-6), and it did not affect the 20:4(n-6) content but decreased the 22:5(n-6) content. ETYA induced an increase of 18:3(n-3) content in the brush border membrane and a decrease of the 22:6(n-3) content in the liver. Those results suggest that ETYA blocks mainly the delta 6-desaturase, which should have two different sites in the liver and one in the intestine.

PubMed Disclaimer

Similar articles

References

    1. Prostaglandins. 1985 Mar;29(3):449-58 - PubMed
    1. J Lipid Res. 1964 Oct;5:600-8 - PubMed
    1. Mol Cell Biochem. 1974 Mar 8;3(1):41-52 - PubMed
    1. Lipids. 1976 Feb;11(2):143-7 - PubMed
    1. Lipids. 1970 May;5(5):494-6 - PubMed

MeSH terms

LinkOut - more resources