Dr Barry Make reports grants, personal fees from Astra Zeneca, personal fees from Spiration, grants, personal fees from Glaxo Smith Kline, personal fees from Mt. Sinai, personal fees from Web MD, personal fees from National Jewish Health, personal fees from Novartis, personal fees from American College of Chest Physicians, personal fees from Projects in Knowledge, personal fees from Medscape, personal fees from Verona, personal fees from Boehringer Ingelheim, personal fees from Mylan, personal fees from Third Pole, personal fees from Phillips, personal fees from Eastern Pulmonary Society, grants from NHLBI, personal fees from Wolters Kluwer Health, personal fees from Optimum Patient Care Global Limited, personal fees from Integritas Communications, personal fees from Quintiles, outside the submitted work. Dr David Mannino reports personal fees from GlaxoSmithKline, outside the submitted work. Dr Fernando Martinez reports grants, personal fees, non-financial support from AstraZeneca, personal fees from Boehringer Ingelheim, grants, COPD Study Steering committee from Chiesi, personal fees from CsL Behring, non-financial support, COPD Ad Board from Gala, grants, non-financial support, COPD Ad Boards, Study Steering Committee, Non-branded presentations; AZ is an independent sponsor of the NHLBI CAPTURE validation study from GlaxoSmithKline, COPD Study adjudication committee from Medtronic, personal fees from Novartis, personal fees from Polarean, COPD Advisory Board from Pulmonx, grants, personal fees from Sanofi/Regeneron, personal fees from Sunovion, personal fees from Teva, personal fees from Theravance/Viatris, COPD Advisory Board from Verona, during the conduct of the study. Dr Meilan K Han reports personal fees from AZ, personal fees from BI, personal fees from Chiesi, personal fees from Cipla, personal fees from GSK, personal fees from Merck, drug supply for clinical trial and clinical trial with funds paid to institution from Novartis, grants from Sunovion, personal fees, consulting and clinical trial with funds paid to institution from Sanofi, personal fees from Teva, personal fees from Verona, outside the submitted work. The authors report no other conflicts of interest in this communication.