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. 2021 Sep 1:14:1149-1153.
doi: 10.2147/CCID.S325858. eCollection 2021.

Characteristics of Grade 2 Disability in Indonesian Children with Leprosy: A Five-Year Multicenter Retrospective Study

Hendra Gunawan  1   2   3 , Atika Kamilia  1   2 , Sri Linuwih Menaldi  2   3   4 , Melani Marissa  2   4 , Cita Rosita Sigit Prakoeswa  2   3   5 , Medhi Denisa Alinda  2   5 , Dhelya Widasmara  2   6 , Santosa Basuki  2   6 , Qaira Anum  2   7 , Tutty Ariani  2   7 , Enricco H Mamuaja  2   8 , Luh Made Mas Rusyati  2   9
Affiliations

Characteristics of Grade 2 Disability in Indonesian Children with Leprosy: A Five-Year Multicenter Retrospective Study

Hendra Gunawan et al. Clin Cosmet Investig Dermatol. .

Abstract

Background: One of the indicators of achieved leprosy control is lower new cases of leprosy with grade 2 disability (G2D), while zero new pediatric case with G2D is one of the targets of The Global Leprosy Strategy. This study aimed to describe the characteristics of leprosy in children with G2D from seven provincial hospitals in Indonesia, spanning a period of five years.

Methods: This was a descriptive and retrospective study with cross-sectional design. Data were obtained from the medical records of leprosy-affected children in seven provincial hospitals in Indonesia between January 2014 and December 2019 using a total sampling method. Data obtained include characteristics of patients, clinical manifestations, and profile of leprosy in children with G2D.

Results: From the 132 data of childhood leprosy retrieved, male (58.33%), age group of 13-14 years (47.73%), and borderline tuberculoid leprosy (34.09%) comprised the majority of patients. Most of the patients had anesthetic macules as the initial manifestation. The results showed 20 (15.15%) children had G2D. Hands were the most common site affected (50.00%), manifested as claw hands, contractures, atrophy of thenar and hypothenar muscles, and pseudomutilation. Foot drop was seen in five (62.50%) children, and lagophthalmos was seen in one child with leprosy.

Conclusion: This study shows that G2D is observed in 15.15% Indonesian children with leprosy at the time of diagnosis, which mostly occurs on the hands in the form of claw hands. Foot disabilities were also observed, most commonly as foot drop, while lagophthalmos was present with disabilities in the eyes. Disability due to leprosy in children really exists. The commitment of all health care services and related institutions is needed in order to reduce the incidence of disability due to leprosy in children.

Keywords: children; grade 2 disability; leprosy.

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Conflict of interest statement

The authors have no conflicts of interest for this work to declare.

References

    1. Salgado CG, de Brito AC, Salgado UI, Spencer JS. Leprosy. In: Kang S, Amagai M, Bruckner AL, et al., editors. Fitzpatrick’s Dermatology in General Medicine. 9th ed. New York: McGraw-Hill; 2019:2892–2919.
    1. Ministry of Health of the Republic of Indonesia. [Infodatin: eliminate stigma and discrimination against leprosy]; 2018. Available from: https://pusdatin.kemkes.go.id.Indonesian.
    1. Lugão HB, Frade MA, Mazzer N, Foss NT, Nogueira-Barbosa MH. Leprosy with ulnar nerve abscess: ultrasound findings in a child. Skeletal Radiol. 2017;46(1):137–140. doi:10.1007/s00256-016-2517-1 - DOI - PubMed
    1. Patil RR. Determinants of leprosy with special focus on children: a socio-epidemiologic perspective. J Eur Acad Dermatol Venereol. 2013;2(2):5–9.
    1. World Health Organization. Global Leprosy (Hansen’s Disease) update, 2018: time to step up prevention initiatives. Wkly Epidemiol Rec. 2020;95(36):417–438.

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