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. 2021 Sep 5:8:2333794X211044796.
doi: 10.1177/2333794X211044796. eCollection 2021.

Properties of Staphylococcus lugdunensis in Children

Fumihiro Ochi  1 , Hisamichi Tauchi  1 , Mari Kagajo  1 , Shinobu Murakami  2 , Hitoshi Miyamoto  2 , Junpei Hamada  1 , Minenori Eguchi-Ishimae  1 , Mariko Eguchi  1
Affiliations

Properties of Staphylococcus lugdunensis in Children

Fumihiro Ochi et al. Glob Pediatr Health. .

Abstract

Background. Staphylococcus lugdunensis is one of the clinically important coagulase-negative staphylococci. The purpose of this study was to elucidate the microbiological features of S. lugdunensis in hospitalized children. Methods. From January 2012 to December 2019, all isolates were retrospectively screened for S. lugdunensis. Results. Twenty-five children were eligible for study. Nineteen and six children were classified into a critical care unit group (Group A) and a general medical ward group (Group B), respectively. The prevalence of methicillin-resistant S. lugdunensis was significantly higher in Group A than in Group B (68.4% vs 0%; P < .01). Eleven children (44%) had S. lugdunensis infections, while the remaining children were colonized. Six of the 11 infected children (55%) had healthcare-associated infections. Moreover, 3 isolates exhibited the methicillin resistance. Conclusions. The bacteriological characteristics of S. lugdunensis differ depending on patient background. Selection of antibiotic treatment should in part rely on patient background data.

Keywords: bacteremia; coagulase-negative staphylococcus; healthcare-associated infection; sepsis.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flow diagram of the Staphylococcus lugdunensis isolates. Flow diagram of the S. lugdunensis isolates included for medical chart review.
See this image and copyright information in PMC

References

    1. Freney J, Brun Y, Bes M, et al.. Staphylococcus lugdunensis sp nov and Staphylococcus schleiferi sp nov, two species from human clinical specimens. Int J Syst Bacteriol. 1988;38:436-439.
    1. Frank KL, Del Pozo JL, Patel R.From clinical microbiology to infection pathogenesis: how daring to be different works for Staphylococcus lugdunensis. Clin Microbiol Rev. 2008;21:111-133. - PMC - PubMed
    1. Sato M, Kubota N, Horiuchi A, Kasai M, Minami K, Matsui H.Frequency, clinical manifestations, and outcomes of Staphylococcus lugdunensis bacteremia in children. J Infect Chemother. 2016;22:298-302. - PubMed
    1. Sowash MG, Uhlemann AC.Community-associated methicillin-resistant Staphylococcus aureus case studies. Methods Mol Biol. 2014;1085:25-69. - PMC - PubMed
    1. Böcher S, Tønning B, Skov RL, Prag J.Staphylococcus lugdunensis, a common cause of skin and soft tissue infections in the community. J Clin Microbiol. 2009;47:946-950. - PMC - PubMed

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