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Case Reports
. 2022;51(7):630-633.
doi: 10.1159/000518229. Epub 2021 Sep 7.

Endotoxin and Cytokine Sequential Hemoadsorption in Septic Shock and Multi-Organ Failure

Juan Carlos Ruiz-Rodríguez  1   2 , Luis Chiscano-Camón  1   2 , Clara Palmada  1   2 , Adolf Ruiz-Sanmartin  1   2 , Marcos Pérez-Carrasco  1   2 , Nieves Larrosa  3 , Juan José González  3 , Manuel Hernández-González  4   5 , Ricard Ferrer  1   2
Affiliations
Case Reports

Endotoxin and Cytokine Sequential Hemoadsorption in Septic Shock and Multi-Organ Failure

Juan Carlos Ruiz-Rodríguez et al. Blood Purif. 2022.

Abstract

The mortality of septic shock remains high [Ann Intensive Care. 2017;7:19], so apart from usual therapy based on source control and antibiotics, some patients may need rescue therapies. Blood purification systems may play a role by facilitating the nonspecific removal of inflammatory mediators and microbiological toxins. There are different hemoadsorption systems, we describe in this case report the sequential use of Polymyxin B (PMX) endotoxin-adsorbing column (Toraymixin PMX-20R; Toray, Tokyo, Japan) and Cytosorb® (Cytosorbents Corp., New Jersey, USA).

Keywords: Endotoxin hemoadsorption; Polymyxin B hemoadsorption; Septic shock.

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