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. 2021 Sep 22;101(9):adv00557.
doi: 10.2340/00015555-3924.

Generalized Nodules and Sclerosis of the Skin: A Quiz

Miriam Mengoni  1 , Andreas Dominik Braun, Evelyn Gaffal
Affiliations

Generalized Nodules and Sclerosis of the Skin: A Quiz

Miriam Mengoni et al. Acta Derm Venereol. .

Abstract

is missing (Quiz).

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Figures

Fig. 1
Fig. 1
Current clinical presentation. Clinical images from the face and left shoulder. Patient consent to publish photographs was obtained.
Fig. 2
Fig. 2
Histopathological aspects of skin biopsies taken at initial and current presentation. Histopathological sections of a skin punch biopsy taken from the forearm at initial presentation showing acanthosis, thickened collagen fibres and dermal mucin deposits (top and mid panel). In comparison, a recent biopsy showed histiocytic-granulomatous infiltrates in the widened dermis (bottom panel). Top and bottom panels stained with haematoxylin and eosin (H&E), mid-panel stained with Alcian Blue. Scale bar: 250 µm.
See this image and copyright information in PMC

References

    1. Rongioletti F, Merlo G, Cinotti E, Fausti V, Cozzani E, Cribier B, et al. . Scleromyxedema: a multicenter study of characteristics, comorbidities, course, and therapy in 30 patients. J Am Acad Dermatol 2013; 69: 66–72. - PubMed
    1. Hoffmann J, Enk A. Skleromyxödem. J Dtsch Dermatol Ges 2020; 18: 1449–1468. - PubMed
    1. Rongioletti F, Merlo G, Carli C, Cribier B, Metze D, Calonje E, et al. . Histopathologic characteristics of scleromyxedema: a study of a series of 34 cases. J Am Acad Dermatol 2016; 74: 1194–1200. - PubMed
    1. Hummers LK. Scleromyxedema. Curr Opin Rheumatol 2014; 26: 658–662. - PubMed
    1. Serra S, Ambrósio C, João Salvador M, Silva J, Serra D, Pedro Reis J, et al. . [A cutaneous thickening case…]. Acta Reumatol Port 2010; 35: 66–71 (in Portuguese). - PubMed