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Case Reports
. 2021 Nov-Dec;44(6):231-234.
doi: 10.1097/WNF.0000000000000478.

Ischemic Stroke and Provoked Seizure as a Manifestation of Brugmansia suaveolens (Angel's Trumpet) Acute Intoxication: A Detailed Clinical, Electroencephalogram, and Magnetic Resonance Imaging Description and 5-Month Follow-up

Eleonora Colosimo  1 , Alessandra Clodomiro, Domenico Pirritano, Alessandra Fratto, Emilio Le Piane, Giovanni Frontera, Domenico Bosco
Affiliations
Case Reports

Ischemic Stroke and Provoked Seizure as a Manifestation of Brugmansia suaveolens (Angel's Trumpet) Acute Intoxication: A Detailed Clinical, Electroencephalogram, and Magnetic Resonance Imaging Description and 5-Month Follow-up

Eleonora Colosimo et al. Clin Neuropharmacol. 2021 Nov-Dec.

Abstract

Methods: We present a detailed clinical, laboratory, electroencephalogram/magnetic resonance imaging description and a 4-month follow-up of a case of stroke and provoked seizures as manifestation of angel's trumpet intoxication.

Results/discussion: A 76-year-old woman presented with stuporous state evolving in 48 hours in bilateral mydriasis, vomiting, global aphasia, confusion, and stereotyped movement. An interictal electroencephalogram, performed 72 hours later, showed frequent generalized epileptiform discharges, and a brain magnetic resonance imaging revealed 2 small subcortical lesions in the right frontal lobe on diffusion weighted imaging sequences. When completely recovered, she could tell that she had mistaken angel's trumpet flowers for pumpkin flowers, so she had eaten them.

Conclusions: Angel's trumpet intoxication is a neurological emergency that deserves attention of both the media in matter of plant poisoning and the scientific forums because of the high lethal potential to better choose the diagnostic and therapeutic process.

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Conflict of interest statement

Conflicts of Interest and Source of Funding: The authors have no conflicts of interest to declare.

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