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. 2021 Sep 15;131(18):e153234.
doi: 10.1172/JCI153234.

Collateral effects of deletion of nlpD on rpoS and rpoS-dependent genes. Reply

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Collateral effects of deletion of nlpD on rpoS and rpoS-dependent genes. Reply

Inès Ambite et al. J Clin Invest. .
No abstract available

Keywords: Bacterial infections; Infectious disease.

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Conflict of interest statement

Conflict of interest: IA and CS are inventors on patents related to the therapeutic use of NlpD (US 16/341,962, Europe 17797991.1, Australia 2017344453, India 20194718316, Singapore 11201903336U). IA and CS are shareholders of SelectImmune Pharma, a biotech startup company developing alternatives to antibiotics in UTI treatment, and CS is chairman of the board.

Figures

Figure 1
Figure 1. Recombinant NlpD treatment accelerated bacterial clearance in CY17-infected C57BL/6 mice (A) and attenuated inflammation (B).
Data are presented as mean ± SEM (n = 5 mice). Two-way ANOVA with Sidak’s multiple comparison tests, *P < 0.05, **P < 0.01, ***P < 0.001.

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