Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec;193(12):4197-4213.
doi: 10.1007/s12010-021-03670-1. Epub 2021 Sep 15.

Recent Advances on Bioactive Ingredients of Morchella esculenta

Haishan Wu  1 , Jing Chen  2   3 , Jinglei Li  4 , Yuting Liu  1 , Hyun Jin Park  5 , Liu Yang  6
Affiliations
Review

Recent Advances on Bioactive Ingredients of Morchella esculenta

Haishan Wu et al. Appl Biochem Biotechnol. 2021 Dec.

Abstract

Morchella esculenta (M. esculenta) is a delicious edible mushroom prized for its special flavor and strong health promoting abilities. Several bioactive ingredients including polysaccharides, polyphenolic compounds, proteins, and protein hydrolysates all contribute to the biological activities of M. esculenta. Different polysaccharides could be extracted and purified depending on the extraction methods and M. esculenta studied. Monosaccharide composition of M. esculenta polysaccharides (MEP) generally includes mannose, galactose, and glucose, etc. MEP possess multiple bioactivities such as antioxidant, anti-inflammation, immunoregulation, hypoglycemic activity, atherosclerosis prevention and antitumor ability. Other components like polyphenols, protein hydrolysates, and several crude extracts are also reported with strong bioactivities. In terms of potential applications of M. esculenta and its metabolites as nutritional supplements and drug supplements, this review aims to comprehensively summarize the structural characteristics, biological activities, research progress, and research trends of the active ingredients produced by M. esculenta. Among the various biological activities, the substances extracted from both natural collected and submerged fermented M. esculenta are promising for antioxidants, immunomodulation, anti-cancer and anti-inflammatory applications. However, further researches on the extraction conditions and chemical structure of bioactive compounds produced by M. esculenta still need investigations.

Keywords: Anticancer; Antioxidant; Bioactivity; Immunomodulatory; Morchella esculenta; Polysaccharides.

PubMed Disclaimer

References

    1. Jahangir, M. M., Khan, A. A., Ali, M. A., Zaif, K., Khan, A., Karim, W., & Samin, G. (2016). The good about Morchella esculenta mushrooms: A review. International Journal of Agricultural and Environmental Research, 2(3), 256–262.
    1. Giavasis, I. (2014). Bioactive fungal polysaccharides as potential functional ingredients in food and nutraceuticals. Current Opinion in Biotechnology, 26C(7), 162–173.
    1. Tietel, Z., & Masaphy, S. (2017). True Morels (Morchella) – Nutritional and phytochemical composition, health benefits and flavor: A review. Critical Reviews in Food Science and Nutrition, 58(11), 1888–1901. - PubMed
    1. Meng, X., Che, C. C., Zhang, J. M., Gong, Z. J., Si, M. R., Yang, G., Cao, L., & Liu, J. F. (2019). Structural characterization and immunomodulating activities of polysaccharides from a newly collected wild Morchella sextelata. International Journal of Biological Macromolecules, 129, 608–614. - PubMed
    1. Heleno, S. A., Stojkovic, D., Barros, L., Glamoclija, J., Sokovic, M., Martins, A., Queiroz, M. J. R. P., & Ferreira, I. C. F. R. (2013). A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia. Food Research International, 51(1), 236–243.

MeSH terms

Supplementary concepts

LinkOut - more resources